TUDCA
A water-soluble bile acid that provides potent support for liver health and cellular function.
Also known as: Tauroursodeoxycholic acid
Overview
TUDCA is a naturally occurring bile acid that plays a crucial role in neutralizing toxic bile acids in the liver. It is highly effective at protecting liver cells from stress, reducing apoptosis (cell death), and improving bile flow, making it a cornerstone supplement for liver detoxification and cholestasis.
Key Benefits
Reduces Liver Enzymes
Clinically shown to significantly lower elevated liver enzymes such as ALT and AST, indicating improved liver health.
Improves Bile Flow
Helps to thin bile and improve its flow, which is crucial for digestion and the elimination of toxins.
Protects Liver Cells
Acts as a chemical chaperone to reduce endoplasmic reticulum (ER) stress, a key factor in liver cell death.
Neuroprotective Effects
Research suggests TUDCA may protect neurons from cell death, showing potential in neurodegenerative diseases.
Dosage & How to Take
250mg taken 1-2 times daily.
| Purpose | Dose | Notes |
|---|---|---|
| General Liver Support | 250-500mg/day | |
| Cholestasis/High Liver Enzymes | 500-1000mg/day | Higher doses are often used in clinical settings. |
Best Time to Take
Can be taken anytime, but some prefer taking it with meals that contain fats to aid digestion.
With or Without Food
Optional.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Synthetic TUDCA | High | Liver and cellular support | Most supplements use a synthetic, stable form of TUDCA. |
Side Effects & Safety
Common
- Generally very well-tolerated.
Rare
- Mild diarrhea at very high doses.
Contraindications
- Bile duct obstruction.
Interactions
May bind to TUDCA and reduce its absorption.
Scientific Research
TUDCA in Primary Biliary Cirrhosis (PBC)
TUDCA has been shown to improve liver biochemistry in patients with PBC, a chronic liver disease.
Food Sources
Products With TUDCA
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.