Riboflavin-5-Phosphate (B2)
The active, bioavailable form of Vitamin B2 for energy and cellular health.
Also known as: R5P • Active B2
Overview
Riboflavin-5-Phosphate (R5P) is the active, coenzyme form of Vitamin B2 (riboflavin). Unlike standard riboflavin, R5P does not need to be converted by the body, making it more readily available for use. It plays a crucial role in energy metabolism, cellular function, and the metabolism of fats and drugs.
Key Benefits
Supports Energy Production
R5P is a key component of the coenzymes FAD and FMN, which are essential for the electron transport chain and cellular energy production.
Promotes Cellular Health
It is involved in the growth, development, and function of cells.
Aids in Red Blood Cell Formation
Riboflavin is necessary for the formation of red blood cells and helps the body use iron.
Acts as an Antioxidant
R5P is involved in the regeneration of glutathione, a powerful antioxidant that protects cells from damage.
Dosage & How to Take
R5P is available in capsule form. The dosage can vary depending on individual needs.
| Purpose | Dose | Notes |
|---|---|---|
| General Health | 25-50mg per day | A common dose for overall health and wellbeing. |
| Migraine Prevention | 400mg per day | Some studies suggest that high doses of riboflavin may help prevent migraines. |
Best Time to Take
Best taken with meals to improve absorption.
With or Without Food
Yes, take with food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Riboflavin-5-Phosphate Capsules | High | Directly providing the active form of B2. | Ideal for individuals with compromised B2 conversion. |
| Riboflavin | Good | General supplementation. | The body must convert it to R5P. |
Side Effects & Safety
Common
- Bright yellow urine (harmless)
Rare
- Diarrhea
- Increased urination
Contraindications
- None known
Interactions
May decrease riboflavin levels.
May decrease the absorption of riboflavin.
Scientific Research
Riboflavin (Vitamin B2) and Health
A review of the role of riboflavin in health and disease.
High-dose riboflavin for migraine prophylaxis: a randomized, controlled trial
This study found that 400mg of riboflavin per day was effective in reducing the frequency of migraines.
Food Sources
Products With Riboflavin-5-Phosphate (B2)
3 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.