Lumbrokinase

A fibrinolytic enzyme from earthworms that supports cardiovascular health.

Also known as: Earthworm enzyme

other Names
Earthworm powder extract
primary Benefits
Supports cardiovascular health, promotes healthy blood circulation.
common Dose
20-40mg per day
best Form
Enteric-coated capsules
timing
On an empty stomach
safety Rating
Moderate Caution

Overview

Lumbrokinase is a group of enzymes extracted from the earthworm Lumbricus rubellus. It has been studied for its fibrinolytic (clot-dissolving) properties. In traditional Chinese medicine, earthworms have been used for centuries to treat various conditions related to blood circulation. Lumbrokinase is believed to work by breaking down fibrin, a protein that forms blood clots. This may help to improve blood flow and reduce the risk of cardiovascular events. It is also being investigated for its potential role in managing biofilm-related infections and for its neuroprotective effects.

Key Benefits

Cardiovascular Support

Helps to break down fibrin and support healthy blood flow.

Biofilm Disruption

May help to break down biofilms, which can protect bacteria from antibiotics.

Neuroprotective Effects

Some research suggests it may have protective effects on the brain.

Dosage & How to Take

It is important to follow the dosage instructions on the product label.

PurposeDoseNotes
Cardiovascular support20-40mgTaken 1-2 times per day.
Biofilm disruption40-60mgTaken under the guidance of a healthcare professional.

Best Time to Take

Best taken on an empty stomach to maximize absorption.

With or Without Food

No

Forms & Bioavailability

FormAbsorptionBest ForNotes
Enteric-coated capsulesHighProtecting the enzyme from stomach acid.The preferred form.

Side Effects & Safety

Common

  • Nausea
  • Diarrhea

Rare

  • Allergic reactions

Contraindications

  • Bleeding disorders, upcoming surgery, and use of anticoagulant drugs.

Interactions

Anticoagulant drugsSevere

Increased risk of bleeding.

Scientific Research

2025PMC

Therapeutic Potential of Lumbrokinase in Acute Ischemic Stroke

Lumbrokinase showed potential in improving neurological function after ischemic stroke.

Food Sources

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.