Artichoke Leaf Extract

A traditional Mediterranean remedy that supports liver health, digestion, and cholesterol management.

Also known as: Cynara scolymus • Cynarin

other Names
Globe Artichoke, Cynara
primary Benefits
Bile production, digestive health, cholesterol support
common Dose
300-600mg daily
best Form
Standardized extract (5% cynarin)
timing
Before meals
safety Rating
Generally safe.

Overview

Artichoke leaf extract is rich in bioactive compounds, most notably cynarin and luteolin. These compounds stimulate bile production, which is essential for digesting fats and eliminating toxins from the liver. It also has antioxidant properties and can help maintain healthy cholesterol levels.

Key Benefits

Stimulates Bile Production

Increases the liver's production of bile, which aids in fat digestion and the absorption of fat-soluble vitamins.

Supports Liver Protection

The antioxidant compounds in artichoke extract protect liver cells from oxidative stress and damage.

Aids Digestion

Can relieve symptoms of indigestion, such as bloating, gas, and nausea, by improving bile flow.

Manages Cholesterol

Studies show it can help lower LDL (bad) cholesterol and increase HDL (good) cholesterol.

Dosage & How to Take

300mg of a standardized extract taken 1-2 times daily before meals.

PurposeDoseNotes
Digestive Aid300-640mg/dayTaken before meals.
Cholesterol Management500-1000mg/dayConsistency is key.

Best Time to Take

Take 15-30 minutes before meals to stimulate bile flow in preparation for digestion.

With or Without Food

No, take before meals.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Standardized Leaf ExtractGoodLiver and digestive supportLook for extracts standardized for their cynarin content (typically 2.5-5%).

Side Effects & Safety

Common

  • Mild gas or bloating.

Rare

  • Allergic reactions in individuals sensitive to the Asteraceae family (ragweed, daisies).

Contraindications

  • Bile duct obstruction, gallstones (consult a doctor).

Interactions

None well-documented.None

Scientific Research

2003Alimentary Pharmacology & Therapeutics

Efficacy of Artichoke Leaf Extract in Dyspepsia

A randomized, double-blind study found that artichoke leaf extract significantly improved symptoms of functional dyspepsia and quality of life compared to placebo.

Food Sources

Artichoke hearts

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.