Arginine
An amino acid that plays a role in blood flow, wound healing, and immune function.
Also known as: L-Arginine
Overview
Arginine, or L-arginine, is a semi-essential amino acid, meaning that the body can produce it, but sometimes needs more than it can make. It is a building block of protein and is involved in many important bodily functions. Arginine is a precursor to nitric oxide (NO), a molecule that helps relax blood vessels and improve blood flow. This has led to its use as a supplement for a variety of conditions related to blood circulation, such as erectile dysfunction and high blood pressure. In addition to its role in blood flow, arginine is also involved in wound healing, immune function, and hormone secretion. It is often used by athletes to improve performance and reduce muscle fatigue, although the evidence for these benefits is mixed. Arginine is found in many protein-rich foods, such as red meat, poultry, fish, and dairy products. As a supplement, it is available in various forms, including capsules, tablets, and powder.
Key Benefits
Improves Blood Flow
Arginine is converted to nitric oxide, which helps relax blood vessels and improve circulation.
May Help with Erectile Dysfunction
By improving blood flow to the penis, arginine may help improve symptoms of erectile dysfunction.
May Enhance Athletic Performance
Some studies suggest that arginine can improve exercise performance and reduce muscle fatigue.
Dosage & How to Take
Start with a lower dose and gradually increase as needed. Consult with a healthcare professional for personalized advice.
| Purpose | Dose | Notes |
|---|---|---|
| Erectile Dysfunction | 5 grams per day | May be taken in divided doses. |
| Athletic Performance | 2-6 grams | Take 30-60 minutes before exercise. |
Best Time to Take
For athletic performance, take before workouts. For other benefits, it can be taken at any time of day.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| L-Arginine | Medium | General use | The most common form of arginine supplement. |
| Arginine AKG | High | Athletic performance | A salt of arginine and alpha-ketoglutarate that may be more easily absorbed. |
Side Effects & Safety
Common
- Nausea
- Diarrhea
- Stomach pain
Rare
- Gout
- Allergic reactions
Contraindications
- Individuals with herpes should use with caution, as arginine may trigger outbreaks.
Interactions
May enhance the effects of these medications
May enhance the effects of these medications
Scientific Research
The effect of L-arginine supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials
L-arginine supplementation may be an effective and safe way to lower blood pressure.
L-arginine for the treatment of erectile dysfunction: a systematic review and meta-analysis
L-arginine may be effective in treating mild to moderate erectile dysfunction.
Food Sources
Products With Arginine
10 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.