7-Keto-DHEA
A non-hormonal metabolite of DHEA that boosts metabolism and promotes fat loss without converting to sex hormones.
Also known as: 7-Oxo-DHEA
Overview
7-Keto-DHEA is a naturally occurring metabolite of dehydroepiandrosterone (DHEA), a hormone produced by the adrenal glands. Unlike DHEA, 7-Keto is non-hormonal, meaning it does not convert into testosterone or estrogen. Its primary benefit for weight management is its ability to increase thermogenesis, the process of producing heat in the body. This boosts the metabolic rate, causing the body to burn more calories throughout the day, even at rest.
Key Benefits
Boosts Resting Metabolic Rate
7-Keto has been shown in clinical studies to increase the resting metabolic rate, helping the body burn more calories.
Promotes Fat Burning
By activating thermogenic enzymes, it encourages the body to use fat stores for energy.
Non-Hormonal Action
Provides metabolic benefits without the potential side effects associated with hormonal supplements like DHEA.
Dosage & How to Take
The standard dose is 100 mg taken twice per day.
| Purpose | Dose | Notes |
|---|---|---|
| Weight Management | 100 mg, 2x daily | Take one dose in the morning and one in the early afternoon. |
Best Time to Take
Avoid taking it late in the evening as the metabolic boost could interfere with sleep.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | Good | Convenience and accurate dosing | The most common form of supplementation. |
Side Effects & Safety
Common
- Generally well-tolerated with few side effects.
Rare
- Headache
- Insomnia
- Increased heart rate
Contraindications
- Pregnancy and breastfeeding
- Thyroid disorders (consult a doctor)
Interactions
May have additive effects. Consult a healthcare provider.
Scientific Research
A randomized, double-blind, placebo-controlled study of 7-keto DHEA in healthy overweight adults
7-Keto DHEA, in conjunction with diet and exercise, produced a significant decrease in body weight and body fat compared to placebo.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.