DHEA
A precursor hormone that supports vitality and well-being.
Also known as: Dehydroepiandrosterone
Overview
Dehydroepiandrosterone (DHEA) is a hormone produced by the adrenal glands, which serves as a precursor to male and female sex hormones, including testosterone and estrogen. Production of DHEA peaks in early adulthood and then gradually declines with age. This decline has led to interest in DHEA supplementation for a variety of age-related conditions. Proponents of DHEA supplements claim that it can improve mood, energy levels, and libido, as well as combat the effects of aging. It is also used to improve skin health, athletic performance, and to support bone density. Research on DHEA has been mixed, with some studies showing benefits for certain conditions, while others have found little to no effect. For example, some research suggests DHEA may help improve mood and reduce symptoms of depression, particularly in individuals with low DHEA levels. However, its effectiveness as an anti-aging supplement remains a topic of debate.
Key Benefits
Supports Hormone Balance
DHEA is a precursor to both testosterone and estrogen, and supplementation may help restore optimal levels of these hormones, particularly in older adults.
Improves Mood and Well-being
Some studies suggest that DHEA may have a positive effect on mood and may help alleviate symptoms of depression.
Enhances Libido
By supporting healthy hormone levels, DHEA may help improve sexual function and desire in both men and women.
Dosage & How to Take
DHEA dosage should be individualized based on age, sex, and health status. It is recommended to start with a low dose and gradually increase as needed.
| Purpose | Dose | Notes |
|---|---|---|
| General Health | 25-50 mg per day | Taken in the morning. |
| Mood Support | 50-100 mg per day | May be divided into two doses. |
Best Time to Take
Best taken in the morning to mimic the body's natural production of DHEA.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | Medium | General use | Micronized forms may have better absorption. |
| Sublingual Tablets | High | Faster absorption | Dissolve under the tongue. |
Side Effects & Safety
Common
- Oily skin
- Acne
- Hair loss
Rare
- Upset stomach
- High blood pressure
Contraindications
- Hormone-sensitive cancers (e.g., breast, prostate)
Interactions
May alter the effects of hormone replacement therapy.
May increase the risk of bleeding.
Scientific Research
DHEA supplementation and its effect on testosterone levels: A systematic review and meta-analysis
DHEA supplementation is effective for increasing testosterone levels, although the magnitude varies among different subgroups.
Dehydroepiandrosterone (DHEA) supplementation in diminished ovarian reserve (DOR)
DHEA improves ovarian function, increases pregnancy chances and, by reducing aneuploidy, lowers miscarriage rates.
Food Sources
Products With DHEA
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.