Back to All ReviewsView on Amazon
#6 in Vitamins Third-Party Tested
Pure Encapsulations B-Complex Plus (120 Capsules)
by Pure Encapsulations
"Methylated B-complex with active folate and B12 — hypoallergenic formula for MTHFR carriers"
Amazon Rating
4.7/5
Reviews
8,200+
Price Range
$34-40
Servings
120 servings
GMP CertifiedHypoallergenicNon-GMO
Our Editorial Rating
8.8
Very Good
Overview
Pure Encapsulations B-Complex Plus provides all 8 B vitamins in their active, methylated forms including methylfolate (Metafolin L-5-MTHF) and methylcobalamin. This is critical for the estimated 40% of the population with MTHFR gene variants who cannot efficiently convert folic acid to its active form. The hypoallergenic formula is free from all major allergens. The 120-capsule count provides a 4-month supply.
Key Ingredients
| Ingredient | Amount |
|---|---|
| Folate (as Metafolin L-5-MTHF) | 400 mcg |
| Vitamin B12 (Methylcobalamin) | 400 mcg |
| Vitamin B6 (as P-5-P) | Included |
| Riboflavin (as R-5-P) | Included |
Pros & Cons
What We Like
- All methylated/active B forms
- Hypoallergenic formula
- 120 capsules = 4-month supply
- Essential for MTHFR carriers
- Pure Encapsulations quality
What Could Be Better
- Premium price $34-40
- Lower doses than some B-complexes
- May not be needed without MTHFR variant
- Most expensive B-complex option
Who Is This For?
Best For
- MTHFR gene variant carriers
- Allergy-sensitive individuals
- Practitioner-recommended B-complex
- Those wanting active B vitamin forms
Not Ideal For
- Budget B-complex seekers
- Those without MTHFR variants
- Those wanting high-dose B vitamins
Our Verdict
8.8/10 — Very Good
The MTHFR carrier's B-complex. Methylated forms bypass the genetic bottleneck that affects 40% of the population. Hypoallergenic quality from the practitioner's brand.