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#3 in Sleep Supplements Third-Party Tested

NOW Foods L-Tryptophan 500mg (120 Veggie Caps)

by NOW Foods

"500mg L-tryptophan per capsule — the serotonin precursor for sleep and mood support with 120 capsules and 8,800+ reviews"

Amazon Rating
4.5/5
Reviews
8,800+
Price Range
$18-24
Servings
120 servings
GMP CertifiedNon-GMONPA A-RatedVegan
Our Editorial Rating
7.8
Good
FormVeggie Capsule
SubcategoryL-Tryptophan (Serotonin Precursor, Sleep)
View on Amazon

Overview

NOW L-Tryptophan 500mg provides the essential amino acid L-tryptophan, which is the direct precursor to serotonin (5-HT) and subsequently melatonin. The conversion pathway is: L-tryptophan → 5-HTP → serotonin → melatonin. Unlike 5-HTP (which bypasses the rate-limiting step), L-tryptophan allows the body to regulate serotonin production naturally through the enzyme tryptophan hydroxylase. Clinical studies show 1-2g of L-tryptophan before bed reduces sleep onset latency (time to fall asleep) by 50% in insomnia patients. L-tryptophan also supports mood, appetite regulation, and pain tolerance through the serotonergic system.

Key Ingredients

IngredientAmount
L-Tryptophan500 mg

1 ingredient linked to detailed encyclopedia profiles

Pros & Cons

What We Like

  • 120 capsules
  • 8,800+ reviews
  • Natural serotonin precursor
  • Body-regulated conversion
  • Under $24

What Could Be Better

  • Takes 30-60 min before bed
  • May interact with SSRIs
  • 500mg (may need 2 caps)
  • Not as fast-acting as melatonin

Who Is This For?

Best For

  • Sleep onset support
  • Mood + sleep dual benefit
  • Those wanting natural sleep aid
  • Those who find melatonin too strong

Not Ideal For

  • Those on SSRIs/MAOIs
  • Those wanting immediate sleep
  • Those wanting melatonin instead
  • Those with carcinoid syndrome

Our Verdict

7.8/10 — Good

NOW L-Tryptophan 500mg is the natural sleep precursor — 500mg of the amino acid that becomes serotonin and then melatonin. Gentler than melatonin with mood benefits; avoid combining with SSRIs.

Alternatives to Consider

No direct alternatives listed for this product yet.