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#24 in Vitamins Third-Party Tested

Nature Made Vitamin B12 1000mcg

by Nature Made

"USP Verified B12 for energy and nerve health — 1000mcg cyanocobalamin from the #1 pharmacist-recommended brand"

Amazon Rating
4.8/5
Reviews
20,000+
Price Range
$10-14
Servings
160 softgels
USP VerifiedGMP Certified
Our Editorial Rating
8.4
Very Good
FormSoftgel
CategoryVitamins
SubcategoryVitamin B12
View on Amazon

Overview

Nature Made Vitamin B12 provides 1000mcg of cyanocobalamin in a USP Verified softgel. Vitamin B12 is essential for energy metabolism, red blood cell formation, neurological function, and DNA synthesis. Deficiency is common in vegetarians/vegans (B12 is found almost exclusively in animal foods), older adults (stomach acid decreases with age, impairing B12 absorption), and those on metformin or proton pump inhibitors. The 1000mcg dose ensures adequate absorption even in those with reduced intrinsic factor.

Key Ingredients

IngredientAmount
Vitamin B12 (Cyanocobalamin)1000 mcg

Pros & Cons

What We Like

  • USP Verified quality
  • 160 softgels (5+ month supply)
  • 1000mcg (overcomes absorption issues)
  • #1 pharmacist-recommended brand
  • 20,000+ Amazon reviews (4.8 stars)

What Could Be Better

  • Cyanocobalamin (not methylcobalamin)
  • Requires conversion to active form
  • Not ideal for MTHFR variants
  • Excess B12 is excreted (water-soluble)

Who Is This For?

Best For

  • Vegetarians and vegans
  • Adults over 50
  • Those on metformin or PPIs
  • Energy and nerve health support

Not Ideal For

  • MTHFR mutation carriers (need methylcobalamin)
  • Those with adequate B12 levels
  • Those wanting active form B12

Our Verdict

8.4/10 — Very Good

Nature Made B12 1000mcg is the mainstream gold standard for B12 supplementation — USP Verified, 160 softgels, and the 4.8-star rating is among the highest on Amazon. For MTHFR carriers, methylcobalamin is preferred, but for the general population, this is excellent.

Alternatives to Consider

No direct alternatives listed for this product yet.