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#2 in Multivitamins Third-Party Tested

Life Extension Two-Per-Day Multivitamin

by Life Extension

"Science-backed multivitamin with premium forms and doses that exceed typical one-a-day formulas by 10-50x"

Amazon Rating
4.6/5
Reviews
14,000+
Price Range
$18-24
Servings
60 servings
GMP CertifiedNon-GMO
Our Editorial Rating
9.2
Excellent
FormCapsule
SubcategoryScience-Based Multivitamin
View on Amazon

Overview

Life Extension Two-Per-Day is consistently rated as one of the best multivitamins by independent reviewers and supplement analysts. It provides dramatically higher doses of key nutrients compared to typical one-a-day multivitamins: 50x more B1, 25x more B6, 12x more B12, 10x more biotin, and 8x more vitamin C compared to Centrum. The formula uses premium ingredient forms including natural mixed tocopherols (vitamin E), 5-MTHF (active folate), methylcobalamin (active B12), and three forms of selenium. Life Extension is a research-focused company that has been publishing peer-reviewed studies since 1980.

Key Ingredients

IngredientAmount
Vitamin C500 mg
Vitamin D32000 IU
5-MTHF (Active Folate)680 mcg DFE
Methylcobalamin (B12)300 mcg
Zinc25 mg

Pros & Cons

What We Like

  • 10-50x higher doses than Centrum
  • Premium bioavailable forms of nutrients
  • Active folate (5-MTHF) for MTHFR carriers
  • Research-backed company since 1980
  • Excellent value for premium ingredients

What Could Be Better

  • Two capsules per day required
  • No iron included (by design)
  • Some nutrients may exceed daily needs
  • Not a one-a-day convenience format

Who Is This For?

Best For

  • Those wanting clinical-dose nutrients
  • MTHFR mutation carriers
  • Health optimization enthusiasts
  • Those upgrading from basic multivitamins

Not Ideal For

  • Those wanting a one-a-day format
  • Those needing iron in their multi
  • People sensitive to high B-vitamin doses

Our Verdict

9.2/10 — Excellent

Life Extension Two-Per-Day is the thinking person's multivitamin. The premium forms and clinical doses put it in a completely different league from drugstore multivitamins. The two-capsule format is a small trade-off for dramatically superior nutrition.

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