Vitamin B6 (as Pyridoxine HCl)
Essential for metabolism, nervous system function, and red blood cell production.
Also known as: Pyridoxine • Pyridoxine Hydrochloride
Overview
Vitamin B6, in the form of Pyridoxine HCl, is a water-soluble vitamin crucial for over 100 enzyme reactions in the body, primarily related to protein metabolism. It also plays a significant role in cognitive development through the biosynthesis of neurotransmitters and in maintaining normal homocysteine levels.
Key Benefits
Supports Brain Function
Plays a vital role in the production of neurotransmitters like serotonin and dopamine, which are important for mood regulation.
Promotes Red Blood Cell Production
Essential for the synthesis of hemoglobin, the protein in red blood cells that carries oxygen throughout the body.
Reduces Homocysteine Levels
Helps to regulate homocysteine levels in the blood, high levels of which are associated with heart disease.
Dosage & How to Take
Dosage varies depending on age, sex, and health conditions. The RDA for adults is 1.3-1.7 mg, but higher doses are used for specific conditions.
| Purpose | Dose | Notes |
|---|---|---|
| General Health | 1.3-1.7 mg/day | Recommended Daily Allowance for adults. |
| Morning Sickness | 10-25 mg, 3-4 times a day | Often used in combination with doxylamine. |
| PMS Symptoms | 50-100 mg/day | May help with mood swings and irritability. |
Best Time to Take
Can be taken at any time of day.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Pyridoxine HCl | High | General supplementation | The most common and well-researched form. |
| Pyridoxal 5'-Phosphate (P-5-P) | High | Individuals with impaired B6 metabolism | The active form of vitamin B6. |
Side Effects & Safety
Common
- Nausea
- Headache
Rare
- Nerve damage (with very high doses)
- Photosensitivity
Contraindications
- Do not take with Levodopa without a decarboxylase inhibitor.
Interactions
Reduces the effectiveness of Levodopa.
May decrease phenytoin levels.
Increases risk of photosensitivity.
Scientific Research
Vitamin B-6 and PMS
Supplementation with vitamin B-6 was associated with a significant reduction in PMS symptoms.
Homocysteine and Cardiovascular Disease
Folic acid, vitamin B12, and vitamin B6 in combination can lower homocysteine levels.
Food Sources
Products With Vitamin B6 (as Pyridoxine HCl)
6 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.