Salidroside (1%)
A potent bioactive compound in Rhodiola rosea with neuroprotective and anti-fatigue properties.
Also known as: Rhodioloside • Rhodiola Rosea Extract
Overview
Salidroside is one of the primary active ingredients in the adaptogenic herb Rhodiola rosea. It is known for its wide range of pharmacological activities, including its ability to combat fatigue, protect the nervous system, reduce inflammation, and act as a powerful antioxidant. Extracts are often standardized to contain at least 1% salidroside.
Key Benefits
Reduces Fatigue and Enhances Performance
Salidroside has been shown to reduce physical and mental fatigue, leading to improved endurance and cognitive function.
Protects the Nervous System
It exhibits neuroprotective effects, potentially helping to protect against age-related cognitive decline and neurodegenerative diseases.
Powerful Antioxidant
Salidroside is a potent antioxidant that can help protect cells from damage caused by free radicals.
Dosage & How to Take
Dosage is typically based on the amount of Rhodiola rosea extract, standardized to 3% rosavins and 1% salidroside. It is best to start with a lower dose and assess tolerance.
| Purpose | Dose | Notes |
|---|---|---|
| Anti-Fatigue | 200-400mg/day | A common effective dose for reducing fatigue. |
| Neuroprotection | 400-600mg/day | Higher doses may be more beneficial for cognitive and neuroprotective effects. |
Best Time to Take
Best taken in the morning and early afternoon to avoid potential sleep disturbances.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Standardized Extract Capsules | High | General use | Look for extracts standardized to 1% salidroside and 3% rosavins for optimal effects. |
| Tincture | High | Faster absorption | A liquid form that may be absorbed more quickly. |
Side Effects & Safety
Common
- Mild jitteriness or overstimulation if taken late in the day
Rare
- Dizziness
- Dry mouth
Contraindications
- Individuals with bipolar disorder should use with caution, as it may trigger manic episodes. Not recommended for pregnant or breastfeeding women.
Interactions
Rhodiola may have MAOI-inhibiting properties and could potentially interact with these medications.
May have an additive effect with other stimulants.
Scientific Research
Salidroside: An Overview of Its Promising Potential and Diverse Pharmacological Properties
Salidroside has significant therapeutic advantages for pulmonary fibrosis, hepatic fibrosis, and renal fibrosis, and is a drug with potential for treating these conditions.
Antioxidant Effects of Salidroside in the Cardiovascular System
Recent studies have shown that salidroside has therapeutic effects, to some degree, in cardiovascular diseases via an antioxidative mechanism.
Food Sources
Products With Salidroside (1%)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.