R5P (Active B2)
The active, readily usable form of Vitamin B2 for enhanced energy and metabolism.
Also known as: Riboflavin 5-Phosphate • Active Vitamin B2
Overview
Riboflavin 5'-Phosphate (R5P) is the active, coenzyme form of Vitamin B2. Unlike standard riboflavin, which requires conversion by the body, R5P is immediately available for use in various metabolic processes, including energy production and the activation of other B vitamins.
Key Benefits
Enhanced Energy Production
R5P is a crucial cofactor in the electron transport chain, the primary pathway for cellular energy (ATP) production.
Improved B-Vitamin Metabolism
It is essential for the conversion of other B vitamins, such as B6 and folate, into their active forms, allowing the body to utilize them effectively.
Supports Methylation
Plays a key role in methylation cycles, which are vital for detoxification, DNA repair, and neurotransmitter synthesis.
Dosage & How to Take
A typical daily dose of R5P is between 25-50mg.
| Purpose | Dose | Notes |
|---|---|---|
| General Health | 25mg | Taken once daily with a meal. |
| Migraine Prevention | Up to 400mg | Should be taken under the guidance of a healthcare professional. |
Best Time to Take
Best taken with a meal to enhance absorption.
With or Without Food
Recommended to be taken with food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | High | Convenience and accurate dosing. | The most common form of R5P supplementation. |
Side Effects & Safety
Common
- Bright yellow urine (harmless)
Rare
- Diarrhea or increased urination at high doses
Contraindications
Interactions
May decrease the absorption of riboflavin from food.
Scientific Research
High-dose riboflavin for migraine prophylaxis in adults
High-dose riboflavin (400mg/day) was effective in reducing migraine frequency.
Food Sources
Products With R5P (Active B2)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.