PQQ (Pyrroloquinoline Quinone)
A novel compound that stimulates the growth of new mitochondria for enhanced cellular energy.
Also known as: BioPQQ • Methoxatin
Overview
PQQ (pyrroloquinoline quinone) is a redox cofactor that acts as an extremely potent antioxidant and stimulates mitochondrial biogenesis — the creation of new mitochondria. It activates PGC-1α, the master regulator of mitochondrial formation. PQQ works synergistically with CoQ10 to optimize cellular energy production.
Key Benefits
Mitochondrial Biogenesis
Stimulates PGC-1α to promote the growth of new mitochondria.
Powerful Antioxidant
Up to 5,000 times more efficient at redox cycling than vitamin C.
Cognitive Support
Improves memory and attention in clinical studies, especially with CoQ10.
Neuroprotection
Protects neurons from oxidative damage and excitotoxicity.
Dosage & How to Take
10-20 mg daily.
| Purpose | Dose | Notes |
|---|---|---|
| General health | 10 mg/day | With food |
| Cognitive support | 20 mg/day | Combined with CoQ10 |
Best Time to Take
Morning with food.
With or Without Food
Yes, with food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| BioPQQ Capsules | Good | Standardized, researched form | Patented form used in studies. |
Side Effects & Safety
Common
- Generally well tolerated
Rare
- Mild headache
- Fatigue initially
Contraindications
- None well-established
Interactions
Works synergistically with CoQ10.
Scientific Research
PQQ and cognitive function
Supplementation with PQQ (20 mg) plus CoQ10 improved cognitive test scores in middle-aged and elderly subjects.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.