Magnesium Orotate

A highly absorbable form of magnesium for heart and muscle health.

other Names
None
primary Benefits
Heart health, muscle function, energy production
common Dose
500-1000 mg per day (providing 31-62 mg of elemental magnesium)
best Form
Capsules or tablets
timing
Can be taken anytime, with or without food
safety Rating
Generally safe, but high doses can cause digestive upset

Overview

Magnesium Orotate is a salt that combines magnesium with orotic acid. This unique combination is thought to enhance the absorption and utilization of magnesium in the body. It is often used to support cardiovascular health, athletic performance, and overall energy production.

Key Benefits

Supports Cardiovascular Health

May help to improve heart function and reduce the risk of heart disease.

Enhances Athletic Performance

Can improve muscle function, reduce fatigue, and support energy production.

Promotes Restful Sleep

Magnesium has a calming effect on the nervous system and can help to improve sleep quality.

Dosage & How to Take

Dosage is based on the total amount of magnesium orotate, not the elemental magnesium content.

PurposeDoseNotes
General Health500 mg/dayA common dose for general support.
Athletic Performance1000 mg/dayA higher dose may be beneficial for athletes.

Best Time to Take

Can be taken at any time of day. Some people prefer to take it before bed for its relaxing effects.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
CapsulesHighConvenience and accurate dosingThe most common form.
TabletsHighConvenience and accurate dosingAnother common form.

Side Effects & Safety

Common

  • Diarrhea
  • nausea
  • stomach cramps (at high doses)

Rare

  • Allergic reactions

Contraindications

  • Kidney disease

Interactions

Tetracycline antibioticsModerate

Magnesium can reduce the absorption of these antibiotics.

BisphosphonatesModerate

Magnesium can interfere with the absorption of these osteoporosis drugs.

Scientific Research

2009International Journal of Cardiology

Magnesium orotate in severe congestive heart failure (MACH)

Magnesium orotate may be used as adjuvant therapy in patients on optimal treatment for severe congestive heart failure, increasing survival rate and improving clinical symptoms.

2022Nutrients

Magnesium Orotate and the Microbiome–Gut–Brain Axis: Modulation in a New Era of Personalized Medicine

The superior benefits of magnesium orotate reside in the better absorption, intra-cellular accumulation of magnesium, improving muscular and neurological outcomes.

Food Sources

Not found in food

Products With Magnesium Orotate

2 products in our database contain this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.