L. fermentum
A versatile probiotic strain known for its immune-boosting and cholesterol-lowering properties.
Also known as: Lactobacillus fermentum
Overview
Lactobacillus fermentum is a species of probiotic bacteria naturally found in the human gut, mouth, and vagina, as well as in fermented foods. It is known for its ability to survive the passage through the gastrointestinal tract and colonize the gut. Research suggests it offers a range of health benefits, including enhancing immune function, improving cholesterol levels, and supporting gut health.
Key Benefits
Enhances Immune Function
Studies show that L. fermentum can modulate the immune system and may reduce the incidence and severity of respiratory infections.
May Lower Cholesterol
Certain strains of L. fermentum have been found to help lower total and LDL (bad) cholesterol levels.
Supports Gut Health
It can help maintain a healthy balance of gut bacteria, inhibit the growth of pathogens, and strengthen the gut barrier.
Possesses Antioxidant Properties
Some strains, like ME-3, are able to produce the powerful antioxidant glutathione, helping to protect the body from oxidative stress.
Dosage & How to Take
The effective dosage of L. fermentum can vary depending on the specific strain and the health condition being targeted.
| Purpose | Dose | Notes |
|---|---|---|
| General Gut Health | 1-10 billion CFU/day | A common dosage for daily maintenance. |
| Immune Support | 10-20 billion CFU/day | Higher doses may be used for specific immune benefits. |
| Cholesterol Reduction | At least 10 billion CFU/day | Specific strains like ME-3 have been studied for this purpose. |
Best Time to Take
Probiotics are generally best taken on an empty stomach, about 30 minutes before a meal.
With or Without Food
Can be taken with a small amount of food if stomach upset occurs.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | Good | General supplementation. | Enteric-coated capsules help protect the probiotics from stomach acid. |
| Powder | Good | Mixing into drinks or food. | Offers dosing flexibility. |
| Fermented Foods | Varies | Dietary source. | Found in foods like sourdough bread, kimchi, and some yogurts. |
Side Effects & Safety
Common
- Mild gas and bloating, especially when first starting.
Rare
- In rare cases, probiotics can cause infections in people with severely compromised immune systems.
Contraindications
- Individuals with compromised immune systems or serious underlying health conditions should consult a doctor before taking probiotics.
Interactions
Antibiotics can kill probiotic bacteria, so it is recommended to take them at least 2-3 hours apart.
Theoretically, probiotics could pose a risk to individuals on immunosuppressive therapy.
Scientific Research
Lactobacillus fermentum ME-3: A new perspective for cardiometabolic health
The ME-3 strain of L. fermentum has been shown to have significant antioxidant and anti-inflammatory effects, with benefits for cardiovascular health.
Probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in marathon runners
Supplementation with L. fermentum CECT5716 was found to reduce the incidence of common infectious diseases in endurance athletes.
Food Sources
Products With L. fermentum
5 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.