Conjugated Linoleic Acid

A fatty acid that may help reduce body fat and increase lean muscle mass.

Also known as: CLA

other Names
CLA
primary Benefits
May reduce body fat, supports lean muscle mass.
common Dose
3-6 grams per day
best Form
Clarinol or Tonalin (branded forms)
timing
With meals
safety Rating
Generally Safe

Overview

Conjugated Linoleic Acid (CLA) is a naturally occurring fatty acid found in meat and dairy products. It is a popular dietary supplement for weight management, believed to aid in reducing body fat (adiposity) and increasing lean body mass. The proposed mechanisms include modulating energy metabolism, reducing fat cell proliferation, and inducing apoptosis in adipocytes.

Key Benefits

Reduces Body Fat

Some studies show that CLA supplementation can lead to a modest reduction in body fat mass in overweight and obese individuals.

Increases Lean Muscle

CLA may help preserve or even increase lean muscle mass during periods of weight loss, which is beneficial for metabolic rate.

Dosage & How to Take

The effective dose of CLA for fat loss appears to be between 3.2 and 6.4 grams per day.

PurposeDoseNotes
Body Fat Reduction3-6 gSplit into 2-3 doses throughout the day.

Best Time to Take

Take with meals to enhance absorption and reduce the risk of gastrointestinal side effects.

With or Without Food

Yes, should be taken with food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Tonalin® CLAHighWeight managementA well-researched, patented form of CLA derived from safflower oil.
Clarinol® CLAHighBody compositionAnother high-quality, patented form of CLA.

Side Effects & Safety

Common

  • Stomach upset
  • Diarrhea
  • Nausea

Rare

  • Fatigue
  • Insulin resistance (at high doses)
  • Fatty liver

Contraindications

  • Diabetes
  • Metabolic syndrome
  • Bleeding disorders

Interactions

Anticoagulant / Antiplatelet drugsModerate

May increase the risk of bleeding.

Scientific Research

2007https://pubmed.ncbi.nlm.nih.gov/17991629/

The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain

CLA supplementation for 6 months was effective in preventing weight and fat mass gain during the holiday season in overweight adults.

Food Sources

Grass-fed beef
Dairy products (milk, cheese)
Lamb

Products With Conjugated Linoleic Acid

2 products in our database contain this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.