Chlorella

The nutrient-dense freshwater algae with unique detoxification and immune-supporting properties

Also known as: Chlorella vulgaris • Chlorella pyrenoidosa • Broken Cell Wall Chlorella

other Names
Chlorella vulgaris, Chlorella pyrenoidosa, Green Algae
primary Benefits
Detoxification, immune support, cholesterol, nutrient density
common Dose
2-5 g daily (tablets or powder)
best Form
Broken cell wall chlorella (C. vulgaris or C. pyrenoidosa)
timing
With meals
safety Rating
Safe (start low to avoid detox reactions)

Overview

Chlorella is a single-celled freshwater green algae that is one of the most nutrient-dense foods on Earth. It contains 50-60% protein by weight, all essential amino acids, chlorophyll (the highest concentration of any plant), vitamins, minerals, and a unique compound called Chlorella Growth Factor (CGF). Chlorella has been extensively studied in Japan, where it is the most popular supplement. Its cell wall binds heavy metals and toxins, making it a popular detoxification agent. Clinical studies show benefits for immune function, cholesterol, blood pressure, and heavy metal excretion. The cell wall must be cracked or broken during processing for the nutrients to be bioavailable — 'broken cell wall' chlorella is the standard.

Key Benefits

Heavy Metal Detoxification

Chlorella's cell wall has a unique ability to bind heavy metals (mercury, lead, cadmium) and other environmental toxins. Animal studies show chlorella reduces heavy metal absorption from food by 40-60% and accelerates excretion. It's commonly used during dental amalgam removal protocols.

Immune System Enhancement

Chlorella stimulates the immune system by increasing natural killer cell activity, interferon production, and T-helper cell counts. A study in healthy adults found 5g/day for 8 weeks significantly increased salivary IgA (mucosal immunity) and NK cell activity.

Cholesterol & Blood Pressure

Clinical trials show chlorella supplementation reduces total cholesterol, LDL, and triglycerides while modestly lowering blood pressure. A meta-analysis found significant reductions in total cholesterol and diastolic blood pressure.

Nutrient Density

Chlorella provides an extraordinary concentration of nutrients: 50-60% complete protein, iron (up to 40% DV per serving), B12 (one of the few plant sources), chlorophyll, omega-3 fatty acids, and Chlorella Growth Factor (CGF) — a nucleotide-peptide complex that may support cellular repair.

Dosage & How to Take

Start with 1g daily and gradually increase to 3-5g over 1-2 weeks. Some protocols use up to 10g daily for detoxification. Start low to minimize detox reactions (headache, GI upset).

PurposeDoseNotes
General health/nutrition2-3 g/dayMaintenance dose for nutrient support
Immune support5 g/dayBased on immune function studies
Detoxification5-10 g/dayHigher doses for active detox protocols. Start low.
Cholesterol support5-10 g/dayBased on clinical trials showing lipid improvements

Best Time to Take

Take with meals. Can be divided into 2-3 doses throughout the day.

With or Without Food

Take with food to improve tolerance and reduce GI upset. The chlorophyll content can cause green-colored stool — this is normal.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Broken Cell Wall TabletsHighConvenience, no tasteCell wall must be broken for nutrient access. Tablets avoid the strong taste.
Broken Cell Wall PowderHighSmoothies, flexible dosingStrong green taste. Mix into smoothies or juice.
Chlorella Growth Factor (CGF) ExtractHighConcentrated active compoundsExtracted nucleotide-peptide complex. More concentrated than whole chlorella.

Side Effects & Safety

Common

  • Green-colored stool (harmless)
  • GI upset when starting (gas, bloating, diarrhea)
  • Detox reactions (headache, fatigue) — start low

Rare

  • Photosensitivity (due to chlorophyll)
  • Allergic reactions
  • Iodine sensitivity (contains trace iodine)

Contraindications

  • Autoimmune diseases (chlorella stimulates immune function)
  • Warfarin use (chlorella contains vitamin K)
  • Iodine sensitivity

Interactions

WarfarinHigh

Chlorella contains vitamin K which can reduce warfarin effectiveness

ImmunosuppressantsModerate

Chlorella stimulates immune function; may counteract immunosuppressive drugs

SpirulinaBeneficial

Often combined for complementary benefits — chlorella for detox, spirulina for energy

Scientific Research

2012Nutrition Journal

Chlorella and Immune Function

5g/day chlorella for 8 weeks significantly increased salivary IgA and NK cell activity in healthy adults

2018Clinical Nutrition

Chlorella and Cholesterol

Meta-analysis found chlorella supplementation significantly reduced total cholesterol and diastolic blood pressure

2009Journal of Medicinal Food

Chlorella and Heavy Metal Detox

Chlorella supplementation reduced mercury levels in dental amalgam patients and accelerated heavy metal excretion

Food Sources

Chlorella is not found in common foods — it is cultivated in controlled freshwater environments and consumed as a supplement

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.