Bitter Orange Extract

A popular ingredient in weight loss supplements, standardized for its synephrine content.

Also known as: Citrus aurantium

other Names
Citrus aurantium, Synephrine
primary Benefits
Weight management, increased energy, appetite control
common Dose
50-100 mg of extract (providing 5-20 mg of synephrine) daily
best Form
Standardized extract (for synephrine)
timing
Before meals or exercise
safety Rating
Generally safe at recommended doses, but can interact with certain medications

Overview

Bitter Orange Extract is derived from the fruit of the Citrus aurantium tree. It contains a compound called synephrine, which is a mild stimulant that can increase metabolism and suppress appetite. It is often used as a safer alternative to ephedra in fat-burning supplements.

Key Benefits

Supports Weight Loss

Bitter Orange Extract can help increase metabolic rate and promote the breakdown of fat.

Reduces Appetite

It may help curb cravings and reduce overall calorie intake.

Enhances Athletic Performance

Its stimulant properties can provide an energy boost for workouts.

Dosage & How to Take

Dosage of Bitter Orange Extract should be based on its synephrine content. It is advisable to start with a low dose.

PurposeDoseNotes
Weight Management50-100 mg of extract (5-20 mg synephrine) dailySplit into 2-3 doses.
Energy Boost50 mg of extract (5-10 mg synephrine)Take 30-60 minutes before activity.

Best Time to Take

Take before meals to help with appetite, or before exercise for energy.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Standardized ExtractHighConsistent synephrine contentLook for extracts standardized to 6-10% synephrine.
CapsulesHighConvenienceEasy to dose and take.

Side Effects & Safety

Common

  • Increased heart rate, jitters, anxiety (especially when combined with caffeine)

Rare

  • Headaches, dizziness, high blood pressure

Contraindications

  • Individuals with heart conditions, high blood pressure, or anxiety disorders should avoid this supplement.

Interactions

MAOIsImportant

Can cause a dangerous rise in blood pressure.

CaffeineModerate

Can amplify the stimulant effects and increase the risk of cardiovascular side effects.

Scientific Research

2012International Journal of Medical Sciences

A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine

The review suggests that p-synephrine from bitter orange is unlikely to cause adverse cardiovascular events at typical doses.

2011Journal of the International Society of Sports Nutrition

The effects of Citrus aurantium extract on body composition and metabolic rate

Supplementation with Citrus aurantium extract led to a significant increase in resting metabolic rate.

Food Sources

Bitter orange fruit

Products With Bitter Orange Extract

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.