Bacillus subtilis

A spore-forming probiotic that supports digestive and immune health.

Also known as: Hay bacillus • Grass bacillus

other Names
Hay bacillus, Grass bacillus
primary Benefits
Digestive health, immune support, gut barrier function
common Dose
1-5 billion CFUs per day
best Form
Spore-based probiotic supplements
timing
With or without meals
safety Rating
Generally considered safe.

Overview

Bacillus subtilis is a species of bacteria that is found in soil and the gastrointestinal tract of humans. It is a spore-forming bacterium, which means it can survive in harsh conditions, such as the acidic environment of the stomach. As a probiotic, Bacillus subtilis has been shown to support digestive health, immune function, and a healthy inflammatory response.

Key Benefits

Supports Digestive Health

Bacillus subtilis can help promote a healthy balance of bacteria in the gut, which can improve digestion and reduce occasional gas and bloating.

Enhances Immune Function

Studies suggest that Bacillus subtilis can stimulate the immune system and help protect against infections.

Strengthens Gut Barrier Function

Bacillus subtilis may help to strengthen the lining of the gut, which can prevent harmful substances from entering the bloodstream.

Dosage & How to Take

A typical daily dose of Bacillus subtilis is 1-5 billion colony-forming units (CFUs).

PurposeDoseNotes
Digestive Health1-5 billion CFUs/dayLook for a high-quality, spore-based probiotic supplement.
Immune Support1-5 billion CFUs/dayConsistency is key for seeing results.

Best Time to Take

Can be taken at any time of day, with or without food.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Spore-Based Probiotic CapsulesHighGeneral useThe spore form allows the bacteria to survive stomach acid and reach the intestines intact.

Side Effects & Safety

Common

  • Mild digestive upset (e.g., gas, bloating) when first starting

Rare

  • None reported

Contraindications

  • Individuals with a compromised immune system should consult a healthcare provider before taking probiotics.

Interactions

AntibioticsModerate

Antibiotics can kill both good and bad bacteria. It is best to take probiotics at least 2 hours apart from antibiotics.

Scientific Research

2017Frontiers in Microbiology

The effect of Bacillus subtilis on the composition and function of the human gut microbiota

Bacillus subtilis supplementation was associated with an increase in beneficial gut bacteria and a decrease in inflammatory markers.

2016Journal of Clinical Immunology

The effects of Bacillus subtilis on the immune system of healthy adults

Bacillus subtilis supplementation was shown to enhance the immune response to a viral challenge.

Food Sources

Natto
Fermented foods

Products With Bacillus subtilis

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.