Saccharomyces boulardii
A unique probiotic yeast that helps prevent and treat diarrhea.
Also known as: S. boulardii
Overview
Saccharomyces boulardii is a beneficial, non-pathogenic yeast that functions as a probiotic. Unlike bacterial probiotics, it is not affected by antibiotics, making it particularly useful for preventing antibiotic-associated diarrhea. It works by crowding out harmful bacteria, neutralizing bacterial toxins, and supporting the health of the intestinal lining. It is one of the most well-researched probiotics for various forms of diarrhea, including traveler's diarrhea and infectious diarrhea.
Key Benefits
Prevents Antibiotic-Associated Diarrhea
Numerous studies confirm its effectiveness when taken alongside antibiotics.
Treats Infectious Diarrhea
Can shorten the duration of diarrhea caused by pathogens like C. difficile and H. pylori.
Supports IBD Remission
May help maintain remission in patients with Crohn's disease and ulcerative colitis.
Dosage & How to Take
5-20 billion CFUs (Colony Forming Units) per day.
| Purpose | Dose | Notes |
|---|---|---|
| Antibiotic-associated diarrhea | 10-20 billion CFUs/day | Start with antibiotics and continue for 1-2 weeks after. |
| Traveler's diarrhea | 5-10 billion CFUs/day | Start 5 days before travel and continue throughout. |
Best Time to Take
Can be taken anytime, with or without food.
With or Without Food
Not necessary.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Freeze-dried capsules | High | All uses | Ensure CFU count is guaranteed through expiry. |
Side Effects & Safety
Common
- Gas
- Bloating
- Constipation
Rare
- Fungemia (in severely immunocompromised patients)
Contraindications
- Severely immunocompromised individuals
- Patients with central venous catheters
Interactions
Will kill S. boulardii, rendering it ineffective.
Scientific Research
S. boulardii for Diarrhea
A meta-analysis of 63 trials found S. boulardii to be significantly effective in preventing and treating various forms of diarrhea with a low risk of side effects.
Food Sources
Products With Saccharomyces boulardii
10 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.