Bacillus clausii
A spore-forming probiotic that supports gut health and immune function.
Also known as: B. clausii
Overview
Bacillus clausii is a beneficial, spore-forming bacterium that is commonly used as a probiotic. Its ability to form spores allows it to survive the acidic environment of the stomach and reach the intestines, where it can help to restore the balance of the gut microbiota. It is often used to treat and prevent diarrhea, including antibiotic-associated diarrhea.
Key Benefits
Treats and Prevents Diarrhea
Bacillus clausii has been shown to be effective in treating and preventing various types of diarrhea, including acute infectious diarrhea and antibiotic-associated diarrhea.
Supports Gut Health
It helps to restore the balance of the gut microbiota, which is essential for proper digestion and overall health.
Modulates the Immune System
Bacillus clausii can help to modulate the immune system, which may be beneficial for individuals with allergies and other immune-related conditions.
Produces Antimicrobial Substances
It produces antimicrobial substances that can help to inhibit the growth of harmful bacteria in the gut.
Dosage & How to Take
The recommended dosage of Bacillus clausii can vary depending on the specific product and the condition being treated. It is typically taken in doses of 2-6 billion CFU (colony-forming units) per day for adults.
| Purpose | Dose | Notes |
|---|---|---|
| Treatment of acute diarrhea | 4-6 billion CFU/day | Taken in divided doses for 5-7 days. |
| Prevention of antibiotic-associated diarrhea | 2-4 billion CFU/day | Taken throughout the course of antibiotic treatment. |
Best Time to Take
Can be taken with or without food.
With or Without Food
Not required.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Oral Suspension | High | Infants, children, and adults who have difficulty swallowing capsules. | The liquid form allows for easy administration. |
| Capsules | High | Adults and older children. | A convenient option for on-the-go use. |
Side Effects & Safety
Common
- Gas and bloating, particularly when first starting to take the probiotic.
Rare
- Allergic reactions in sensitive individuals.
Contraindications
- Individuals with a known allergy to Bacillus clausii or any other component of the product.
Interactions
Antibiotics can reduce the effectiveness of Bacillus clausii. It is recommended to take the probiotic at least 2-3 hours apart from antibiotics.
Scientific Research
Bacillus clausii for the Treatment of Acute Diarrhea in Children
A meta-analysis of randomized controlled trials found that Bacillus clausii was effective in reducing the duration of diarrhea and the frequency of stools in children with acute diarrhea.
Prophylactic Use of Bacillus clausii in the Prevention of Antibiotic-Associated Diarrhea
A randomized controlled trial found that prophylactic use of Bacillus clausii significantly reduced the incidence of antibiotic-associated diarrhea in adults.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.