NOW Foods D-Mannose 500mg
by NOW Foods
"Natural UTI prevention — 500mg D-mannose that prevents E. coli from adhering to urinary tract walls"
Overview
NOW Foods D-Mannose provides 500mg of D-mannose per capsule — a naturally occurring simple sugar that prevents urinary tract infections (UTIs) by a unique mechanism. E. coli bacteria (responsible for 80-90% of UTIs) have fimbriae (hair-like structures) that bind to mannose receptors on urinary tract walls. When D-mannose is present in urine, E. coli preferentially bind to the free D-mannose instead of the urinary tract wall, and are flushed out during urination. Clinical studies show D-mannose is as effective as antibiotics for UTI prevention with none of the antibiotic resistance concerns.
Key Ingredients
| Ingredient | Amount |
|---|---|
| D-Mannose | 500 mg |
Pros & Cons
What We Like
- Prevents E. coli adhesion (UTI prevention)
- As effective as antibiotics in studies
- No antibiotic resistance concerns
- 120 capsules per bottle
- 10,000+ Amazon reviews
What Could Be Better
- Only effective against E. coli UTIs
- 500mg per capsule (clinical dose is 2000mg)
- Need 4 capsules for clinical dosing
- Not a treatment for active UTI
Who Is This For?
Best For
- Recurrent UTI prevention
- Women prone to UTIs
- Those wanting antibiotic alternative
- Post-intercourse UTI prevention
Not Ideal For
- Active UTI treatment (see doctor)
- Non-E. coli UTIs
- Those wanting single-capsule dosing
Our Verdict
NOW D-Mannose is the natural, evidence-based UTI prevention supplement. The mechanism is elegant — E. coli bind to free D-mannose instead of urinary tract walls. For women with recurrent UTIs, this is a game-changing alternative to prophylactic antibiotics.
Alternatives to Consider
No direct alternatives listed for this product yet.