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#2 in Herbal Supplements Third-Party Tested

Life Extension Super R-Lipoic Acid 240mg (60 Capsules)

by Life Extension

"240mg Bio-Enhanced R-lipoic acid (not racemic) — the mitochondrial antioxidant that regenerates vitamins C, E, and glutathione"

Amazon Rating
4.5/5
Reviews
3,800+
Price Range
$28-36
Servings
60 servings
GMP CertifiedNon-GMO
Our Editorial Rating
8.2
Very Good
FormCapsule
SubcategoryR-Lipoic Acid (Mitochondrial, Antioxidant)
View on Amazon

Overview

Life Extension Super R-Lipoic Acid provides 240mg of Bio-Enhanced R-lipoic acid per capsule. This is the R-isomer only — not the racemic (R/S) alpha-lipoic acid found in most supplements. The R-isomer is the biologically active form that the body naturally produces, and it's 12x more bioavailable than racemic ALA. R-lipoic acid is unique among antioxidants because it's both water-soluble and fat-soluble, allowing it to work in every compartment of the cell. It also regenerates other antioxidants (vitamins C, E, CoQ10, and glutathione) back to their active forms. R-lipoic acid is a cofactor for mitochondrial enzymes (pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase), directly supporting ATP production.

Key Ingredients

IngredientAmount
Bio-Enhanced R-Lipoic Acid240 mg

1 ingredient linked to detailed encyclopedia profiles

Pros & Cons

What We Like

  • R-isomer only (12x more bioavailable)
  • 60 capsules
  • Regenerates other antioxidants
  • Mitochondrial support
  • Both water and fat soluble

What Could Be Better

  • Premium price ($28+)
  • 3,800+ reviews (niche)
  • May lower blood sugar
  • Take on empty stomach for best absorption

Who Is This For?

Best For

  • Mitochondrial health
  • Those wanting master antioxidant
  • Blood sugar support
  • Anti-aging protocols

Not Ideal For

  • Budget seekers
  • Those on blood sugar medications
  • Those wanting racemic ALA
  • Casual antioxidant supplementation

Our Verdict

8.2/10 — Very Good

Life Extension Super R-Lipoic Acid is the mitochondrial antioxidant — 240mg of the bioactive R-isomer that regenerates vitamins C, E, and glutathione. The premium for R-isomer over racemic ALA is justified by 12x higher bioavailability.

Alternatives to Consider

No direct alternatives listed for this product yet.