Vitamin K1 (Phylloquinone)
The essential vitamin for blood clotting and bone health.
Also known as: Phylloquinone • Phytonadione
Overview
Vitamin K1, also known as phylloquinone, is a fat-soluble vitamin primarily found in leafy green vegetables. It plays a crucial role in blood coagulation by activating proteins required for blood clotting. It also participates in bone metabolism and helps maintain bone density.
Key Benefits
Essential for Blood Clotting
Vitamin K1 is necessary for the synthesis of several proteins involved in the blood clotting cascade, preventing excessive bleeding.
Supports Bone Health
It helps activate osteocalcin, a protein that binds calcium to the bone matrix, contributing to bone strength and density.
May Promote Heart Health
By helping to prevent the calcification of arteries, Vitamin K1 may play a role in maintaining cardiovascular health.
Dosage & How to Take
The recommended daily intake for adults is 90 mcg for women and 120 mcg for men. Higher doses may be used for specific medical conditions under a doctor's supervision.
| Purpose | Dose | Notes |
|---|---|---|
| General Health | 90-120 mcg per day | Adequate intake for most adults. |
| To counteract warfarin | 1-10 mg per day | Used under medical supervision to manage anticoagulant effects. |
Best Time to Take
Best taken with a meal that includes some fat to maximize absorption.
With or Without Food
Should be taken with food, especially fats.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Phylloquinone (K1) | Medium | General supplementation and dietary intake. | Found in leafy greens and supplements. |
| Menaquinone (K2) | High | Bone and cardiovascular health. | Found in fermented foods and animal products. |
Side Effects & Safety
Common
- Generally well-tolerated
Rare
- Allergic reactions to supplements
Contraindications
- Individuals taking anticoagulant medications (blood thinners) like warfarin should consult their doctor before taking Vitamin K supplements.
Interactions
Vitamin K can decrease the effectiveness of warfarin, increasing the risk of clotting.
Can reduce the absorption of fat-soluble vitamins, including Vitamin K.
Scientific Research
Vitamin K and bone health: a review of the evidence
Evidence suggests that Vitamin K plays an important role in maintaining bone health and reducing the risk of fractures.
The role of vitamin K in cardiovascular health: a review of the literature
Vitamin K may help to prevent vascular calcification, a risk factor for cardiovascular disease.
Food Sources
Products With Vitamin K1 (Phylloquinone)
5 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.