Valine

An essential branched-chain amino acid (BCAA) that promotes muscle growth and repair.

Also known as: L-Valine

other Names
L-Valine
primary Benefits
Muscle growth, tissue repair, energy production, nitrogen balance
common Dose
5-10 grams per day
best Form
Free-form L-Valine or as part of a BCAA complex
timing
Intra-workout or post-workout
safety Rating
Generally safe for most adults

Overview

Valine is one of the three branched-chain amino acids (BCAAs), essential for muscle protein synthesis, tissue regeneration, and energy production. It works in conjunction with leucine and isoleucine to support muscle health and athletic performance. Valine is also involved in nitrogen balance and cognitive function.

Key Benefits

Stimulates Muscle Growth

Valine plays a crucial role in muscle protein synthesis, the process of building new muscle tissue.

Enhances Tissue Repair

It aids in the repair of damaged tissues, including muscles, making it beneficial for post-workout recovery.

Provides Energy

Valine can be used as an energy source by muscles during exercise, sparing other energy stores.

Maintains Nitrogen Balance

Valine is important for maintaining a positive nitrogen balance, which is essential for muscle growth and preventing muscle breakdown.

Dosage & How to Take

Valine is commonly taken as part of a BCAA supplement, with a typical ratio of 2:1:1 (Leucine:Isoleucine:Valine). The dosage can be adjusted based on individual goals and activity levels.

PurposeDoseNotes
General Health1-2 grams per dayCan be obtained through a protein-rich diet.
Athletic Performance5-10 grams per dayOften taken as part of a BCAA supplement around workouts.

Best Time to Take

For optimal results, consume Valine during or after your workout.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
L-ValineHighGeneral supplementationThe most common and well-researched form.
BCAA ComplexHighAthletic performanceProvides a balanced ratio of Isoleucine, Leucine, and Valine.

Side Effects & Safety

Common

  • Nausea
  • Stomach upset

Rare

  • Fatigue
  • Headache

Contraindications

  • Mayple syrup urine disease (MSUD)

Interactions

Leucine and IsoleucineMild

Competes for absorption, so it's best to take them in a balanced ratio.

Diabetes medicationsModerate

May enhance the effects of medications that lower blood sugar.

Scientific Research

2018The Journal of Nutrition

The role of valine in muscle protein synthesis

Valine supplementation was shown to increase the rate of muscle protein synthesis in healthy adults.

2020International Journal of Sport Nutrition and Exercise Metabolism

BCAA supplementation and exercise-induced muscle damage

Supplementing with BCAAs, including valine, reduced markers of muscle damage and soreness after intense exercise.

Food Sources

Beef
Chicken
Pork
Fish
Soybeans

Products With Valine

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.