Type 2 Collagen

The primary collagen in cartilage, essential for joint health and mobility.

Also known as: Collagen Type II • Undenatured Type II Collagen (UC-II)

other Names
Collagen Type II, Undenatured Type II Collagen (UC-II)
primary Benefits
Joint health, reduced joint pain and stiffness
common Dose
40 mg of UC-II per day
best Form
Undenatured Type II Collagen (UC-II)
timing
Any time of day
safety Rating
Generally safe for most people

Overview

Type 2 collagen is the main structural protein in cartilage, the flexible tissue that cushions our joints. It is what gives cartilage its strength and elasticity. As we age, or due to conditions like osteoarthritis, the cartilage in our joints can break down, leading to pain, stiffness, and reduced mobility. Supplementing with Type 2 collagen, particularly in its undenatured form (UC-II), can help to reduce joint inflammation and support cartilage repair.

Key Benefits

Reduces Joint Pain and Stiffness

Has been shown to be effective in reducing joint pain and stiffness associated with osteoarthritis.

Supports Cartilage Health

May help to protect and repair cartilage by reducing inflammation and promoting the production of new cartilage.

Improves Joint Mobility

By reducing pain and inflammation, Type 2 collagen can help to improve joint mobility and function.

Dosage & How to Take

The standard dose for undenatured Type 2 collagen (UC-II) is 40 mg per day.

PurposeDoseNotes
Joint Health40 mg of UC-IITaken once daily.

Best Time to Take

Can be taken any time of day, with or without food.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Undenatured Type II Collagen (UC-II)HighJoint healthThe most researched and effective form of Type 2 collagen for joint support.
Hydrolyzed Type 2 CollagenMediumGeneral cartilage supportMay not be as effective as UC-II for reducing inflammation.

Side Effects & Safety

Common

  • None known

Rare

  • Allergic reactions

Contraindications

  • Individuals with a chicken allergy should avoid this product.

Interactions

None knownMild

No significant interactions have been reported.

Scientific Research

2013Journal of the International Society of Sports Nutrition

Undenatured type II collagen (UC-II) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers

A 2013 study found that UC-II was effective in improving joint comfort, flexibility, and mobility in healthy adults.

2016Nutrition Journal

Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study

A 2016 study found that UC-II was more effective than glucosamine and chondroitin in reducing pain and stiffness in individuals with osteoarthritis of the knee.

Food Sources

Chicken cartilage

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.