Tocotrienols

The lesser-known form of vitamin E with 40-60x greater antioxidant potency than tocopherols.

Also known as: Annatto Tocotrienols • Delta-Tocotrienol • DeltaGold

other Names
Annatto Tocotrienols, Delta-Tocotrienol, DeltaGold
primary Benefits
Cardiovascular, neuroprotection, skin health, antioxidant
common Dose
100-300 mg daily
best Form
Annatto-derived (tocopherol-free)
timing
With a fat-containing meal
safety Rating
Very Safe

Overview

Tocotrienols are a group of four compounds (alpha, beta, gamma, delta) that make up half of the vitamin E family. Unlike the more common tocopherols, tocotrienols have an unsaturated side chain that allows them to move more freely through cell membranes. They are 40-60x more potent as antioxidants and have unique benefits for cardiovascular health, brain protection, and skin health.

Key Benefits

Cardiovascular Health

Reduces LDL cholesterol, triglycerides, and arterial stiffness.

Neuroprotection

Protects brain cells from glutamate-induced toxicity and oxidative damage.

Skin Health

Protects against UV damage and supports skin elasticity.

Bone Health

Studies show tocotrienols support bone mineral density.

Dosage & How to Take

100-300 mg daily.

PurposeDoseNotes
General antioxidant100-150 mg/dayMixed tocotrienols
Cardiovascular support200-300 mg/dayAnnatto-derived preferred

Best Time to Take

With a fat-containing meal.

With or Without Food

Yes, always with dietary fat.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Annatto-Derived SoftgelsHighTocopherol-free formulaContains only delta and gamma tocotrienols.
Palm-Derived CapsulesGoodFull-spectrumContains all four tocotrienols plus tocopherols.
Rice Bran-DerivedGoodAlternative sourceLower concentration.

Side Effects & Safety

Common

  • Generally very well tolerated

Rare

  • Mild GI discomfort at high doses

Contraindications

  • Concurrent high-dose vitamin E (tocopherols may compete)

Interactions

Blood thinnersMild

May have mild anticoagulant effects.

Statin drugsMild

May have synergistic cholesterol-lowering effects.

Scientific Research

2020Nutrition Reviews

Tocotrienols and cardiovascular health

Meta-analysis showed significant reductions in total cholesterol, LDL, and triglycerides.

Food Sources

Annatto seeds
Palm oil
Rice bran oil
Barley

Products With Tocotrienols

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.