Sulforaphane (from Broccoli Seed Extract)
A powerful antioxidant and anti-inflammatory compound found in cruciferous vegetables.
Also known as: SFN • Glucoraphanin
Overview
Sulforaphane is a sulfur-rich compound found in cruciferous vegetables like broccoli. It is known for its potent antioxidant and anti-inflammatory properties, and has been studied for its potential to prevent and treat various chronic diseases.
Key Benefits
Powerful Antioxidant
Activates the Nrf2 pathway, which upregulates the production of antioxidant enzymes in the body.
Anti-Inflammatory Effects
Inhibits the NF-κB pathway, a key regulator of inflammation.
Supports Detoxification
Enhances the body's natural detoxification processes by inducing phase II detoxification enzymes.
Dosage & How to Take
Dosage can vary depending on the desired effect. It is best to start with a lower dose and gradually increase as tolerated.
| Purpose | Dose | Notes |
|---|---|---|
| General Antioxidant Support | 10-20 mg/day | A good starting dose for most people. |
| Joint Health | 20-40 mg/day | May help to reduce inflammation and pain. |
| Cancer Prevention | 40-60 mg/day | Higher doses are being studied for their potential anti-cancer effects. |
Best Time to Take
Can be taken at any time of day.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Broccoli Seed Extract | High | General supplementation | Look for extracts standardized for sulforaphane or glucoraphanin content. |
| Stabilized Sulforaphane | High | Maximum potency | A more direct and potent form of sulforaphane. |
Side Effects & Safety
Common
- Gas
- Bloating
- Diarrhea
Rare
- Stomach cramps
Contraindications
- None known.
Interactions
May increase the risk of bleeding.
May alter the activity of enzymes involved in drug metabolism.
Scientific Research
Sulforaphane and Cancer
Sulforaphane has been shown to inhibit the growth of cancer cells and induce apoptosis (cell death) in various types of cancer.
Sulforaphane and Autism
A small study found that sulforaphane from broccoli sprout extract improved social interaction and verbal communication in young men with autism.
Food Sources
Products With Sulforaphane (from Broccoli Seed Extract)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.