Sesame Lignans

Antioxidant compounds from sesame seeds that support liver health and fat metabolism.

Also known as: Sesamin • Sesamolin

other Names
Sesamin, Sesamolin
primary Benefits
Antioxidant support, liver health, fat metabolism, cholesterol support
common Dose
50-100 mg per day
best Form
Standardized extract in softgels
timing
With meals
safety Rating
Generally safe and well-tolerated.

Overview

Sesame lignans are a group of beneficial compounds found in sesame seeds, with sesamin and sesamolin being the most prominent. They are known for their potent antioxidant properties, ability to support liver health, and role in promoting healthy fat metabolism. Sesame lignans may also help maintain healthy cholesterol levels already within the normal range.

Key Benefits

Powerful Antioxidant Effects

Sesame lignans help to increase the body's levels of vitamin E and other antioxidants, protecting against oxidative stress.

Supports Liver Health

They enhance the liver's ability to break down fatty acids and can protect liver cells from damage.

Promotes Fat Burning

Sesamin has been shown to increase the activity of enzymes involved in fatty acid oxidation (fat burning).

Dosage & How to Take

Supplements are typically standardized for their sesamin content, with doses ranging from 50-100 mg per day.

PurposeDoseNotes
General Antioxidant Support50mg per dayTake with a meal.
Fat Metabolism Support100mg per dayOften taken in combination with other fat loss supplements like fish oil.

Best Time to Take

Best taken with meals, particularly those containing fats.

With or Without Food

Should be taken with food to enhance absorption.

Forms & Bioavailability

FormAbsorptionBest ForNotes
SoftgelsHighConvenience and stabilityOften combined with other oils like fish oil.
PowderMediumMixing into foodLess common than softgels.

Side Effects & Safety

Common

  • None known at recommended doses.

Rare

  • Allergic reactions in individuals with sesame allergies.

Contraindications

  • Individuals with a sesame allergy should avoid this supplement.

Interactions

Blood pressure medicationModerate

Sesame lignans may have a mild blood pressure-lowering effect and could amplify the effects of antihypertensive drugs.

Scientific Research

1991Journal of Atherosclerosis and Thrombosis

The effect of sesamin on lipid metabolism in rats

Sesamin was found to inhibit cholesterol absorption and synthesis, as well as increase fatty acid oxidation.

Food Sources

Sesame seeds
Sesame oil

Products With Sesame Lignans

4 products in our database contain this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.