Palmitoylethanolamide
A natural pain reliever and anti-inflammatory.
Also known as: PEA
Overview
Palmitoylethanolamide (PEA) is a fatty acid amide that is naturally produced by the body. It is involved in a variety of physiological processes, including pain, inflammation, and immunity. PEA has been shown to have analgesic, anti-inflammatory, and neuroprotective properties. It is a popular supplement for the treatment of chronic pain, as well as other conditions, such as fibromyalgia, osteoarthritis, and multiple sclerosis.
Key Benefits
Relieves Pain
PEA has been shown to be effective in the treatment of a variety of pain conditions.
Reduces Inflammation
PEA has anti-inflammatory properties that may help to reduce inflammation throughout the body.
Protects the Nervous System
PEA has neuroprotective properties that may help to protect the nervous system from damage.
Dosage & How to Take
Start with a low dose and gradually increase as tolerated.
| Purpose | Dose | Notes |
|---|---|---|
| Pain Relief | 600-1200mg daily | Taken in divided doses. |
| General Health | 300-600mg daily | Taken with or without food. |
Best Time to Take
Can be taken with or without food.
With or Without Food
Either
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | High | Convenience and precise dosing. | |
| Powder | High | Can be mixed with water or other beverages. |
Side Effects & Safety
Common
- Dizziness
- Headaches
Rare
- Nausea
- Stomach upset
Contraindications
Interactions
Scientific Research
The effect of palmitoylethanolamide on chronic pain
PEA supplementation was effective in reducing pain in a study of people with chronic pain.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.