Oleuropein
Powerful olive-derived polyphenol with cardiovascular and antimicrobial benefits.
Also known as: Olive Leaf Extract • Olive Polyphenol • Olea europaea Extract
Overview
Oleuropein is the primary bioactive polyphenol found in olive leaves, olive oil, and olive fruit. It is responsible for many of the health benefits attributed to the Mediterranean diet, including cardiovascular protection, blood pressure regulation, antimicrobial activity, and potent antioxidant effects.
Key Benefits
Blood Pressure Reduction
Relaxes blood vessels through nitric oxide-mediated vasodilation, comparable to some antihypertensive medications.
Cardiovascular Protection
Reduces LDL oxidation, improves endothelial function, and supports healthy cholesterol levels.
Potent Antioxidant
Scavenges free radicals with an ORAC value significantly higher than vitamin C and green tea.
Antimicrobial Activity
Effective against a broad spectrum of bacteria, viruses, and fungi including influenza and herpes simplex.
Dosage & How to Take
500-1000mg of olive leaf extract standardized to 6-20% oleuropein, taken 1-2 times daily with meals.
| Purpose | Dose | Notes |
|---|---|---|
| General antioxidant support | 500mg daily | Standardized to 6% oleuropein |
| Blood pressure support | 500-1000mg twice daily | Standardized to 15-20% oleuropein |
| Immune support | 750-1000mg daily | Higher oleuropein concentration preferred |
Best Time to Take
With meals to improve absorption and reduce stomach irritation
With or Without Food
Yes, recommended with food
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Standardized Olive Leaf Extract | High | Consistent dosing | Look for 15-20% oleuropein standardization |
| Liquid Extract | Very High | Rapid absorption | Can have bitter taste |
| Extra Virgin Olive Oil | Medium | Dietary intake | Lower concentration but whole-food matrix |
Side Effects & Safety
Common
- Mild stomach discomfort
- Headache (Herxheimer reaction initially)
Rare
- Dizziness from blood pressure reduction
- Allergic reactions
Contraindications
- Olive allergy
Interactions
May enhance hypotensive effects
May lower blood sugar levels
Mild antiplatelet activity
Scientific Research
Olive Leaf Extract vs. Captopril
Olive leaf extract (500mg twice daily) was as effective as captopril 12.5mg for reducing blood pressure over 8 weeks
Oleuropein Antioxidant Capacity
Oleuropein demonstrated 400% greater antioxidant capacity than vitamin C in vitro
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.