Nicotinamide Riboside

A form of vitamin B3 that boosts NAD+ levels for healthy aging.

Also known as: NR • Niagen

other Names
Niagen
primary Benefits
Healthy aging, cellular energy, DNA repair
common Dose
250-500 mg per day
best Form
Capsules
timing
Can be taken anytime
safety Rating
Generally Safe

Overview

Nicotinamide riboside (NR) is a unique member of the vitamin B3 family. It is a precursor to nicotinamide adenine dinucleotide (NAD+), a vital coenzyme found in every cell of the body. NAD+ plays a crucial role in cellular energy production, DNA repair, and many other metabolic processes. As we age, NAD+ levels naturally decline, which is believed to contribute to the aging process and age-related health issues. By boosting NAD+ levels, NR is thought to support healthy aging and cellular function. It has been studied for its potential benefits in a wide range of areas, including cardiovascular health, cognitive function, and metabolic health. NR is a popular supplement for those looking to support their overall health and well-being as they age.

Key Benefits

Boosts NAD+ Levels

NR is efficiently converted to NAD+ in the body, helping to replenish declining levels of this crucial coenzyme.

Supports Cellular Energy Production

By increasing NAD+ levels, NR can enhance the production of ATP, the body's primary energy currency.

Promotes Healthy Aging

By supporting cellular health and function, NR may help to mitigate some of the effects of aging.

Dosage & How to Take

The recommended dose of NR can vary, but most studies have used doses in the range of 250-500 mg per day.

PurposeDoseNotes
General health and wellness250-300 mg per dayA good starting dose for most people.
More intensive supportUp to 1,000 mg per dayHigher doses have been used in some studies, but it is best to consult with a healthcare provider.

Best Time to Take

NR can be taken with or without food.

With or Without Food

Can be taken with or without food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
CapsulesHighGeneral useThe most common and convenient form.
PowderHighMixing into drinksCan be added to water or other beverages.

Side Effects & Safety

Common

  • Mild nausea
  • Headache

Rare

  • None reported in most studies

Contraindications

  • None known.

Interactions

None knownMild

NR is generally considered safe and well-tolerated.

Scientific Research

2018Nature Communications

Nicotinamide riboside is a safe and effective NAD+ booster in healthy middle-aged and older adults

A randomized, double-blind, placebo-controlled study found that NR supplementation significantly increased NAD+ levels and was well-tolerated.

2019Nutrients

The emerging role of nicotinamide riboside in health and disease

A review of the literature on NR, highlighting its potential benefits for a variety of health conditions.

Food Sources

Milk
Yeast
Beer

Products With Nicotinamide Riboside

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.