Nicotinamide

A form of Vitamin B3 that supports skin health by improving barrier function, reducing inflammation, and minimizing pores.

Also known as: Niacinamide • Vitamin B3

other Names
Niacinamide, Vitamin B3
primary Benefits
Anti-inflammatory, barrier support, pore reduction
common Dose
500 mg, once or twice daily (oral)
best Form
Nicotinamide (non-flushing)
timing
Anytime
safety Rating
Generally Safe

Overview

Nicotinamide, also known as niacinamide, is a form of Vitamin B3. It is a versatile ingredient that offers numerous benefits for the skin, whether applied topically or taken orally. It plays a crucial role in cellular energy production and repair. Nicotinamide helps to build proteins in the skin, including keratin, and locks in moisture to prevent environmental damage. It can reduce inflammation, which may help ease redness from eczema and acne. It also has been shown to reduce the appearance of pore size and regulate oil production.

Key Benefits

Improves Epidermal Barrier Function

It increases the production of ceramides, resulting in a stronger, healthier skin barrier and better hydration.

Reduces Redness and Inflammation

Its anti-inflammatory properties make it effective for calming irritated skin and conditions like acne and rosacea.

Minimizes Pore Appearance

It can help to regulate sebum production and improve skin elasticity, which can make pores appear smaller.

Dosage & How to Take

For oral supplementation, 500 mg once or twice daily is a common dose for skin health.

PurposeDoseNotes
General Skin Health500 mg/day
Acne or Inflammatory Conditions500 mg twice a day

Best Time to Take

Can be taken with or without food.

With or Without Food

Not necessary.

Forms & Bioavailability

FormAbsorptionBest ForNotes
NicotinamideHighOral and topical useThis form does not cause the 'niacin flush' associated with nicotinic acid.
Topical NiacinamideDirectTargeted treatmentSerums with 5-10% niacinamide are very popular and effective.

Side Effects & Safety

Common

  • Generally very well-tolerated.

Rare

  • High doses (>3g/day) may cause nausea or indigestion.

Contraindications

  • None at standard doses.

Interactions

Scientific Research

2005Dermatologic Surgery

Niacinamide: A B vitamin that improves aging facial skin appearance

A study on topical 5% niacinamide showed significant improvements in fine lines, wrinkles, hyperpigmentation spots, red blotchiness, and skin elasticity.

Food Sources

Tuna
Chicken breast
Turkey
Avocado
Green peas

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.