Maitake Mushroom

A medicinal mushroom that supports immune function and blood sugar balance.

Also known as: Grifola frondosa • Hen of the woods

other Names
Hen of the woods, ram's head, sheep's head
primary Benefits
Supports immune function, helps regulate blood sugar, may have anti-cancer properties.
common Dose
1-3 grams of dried mushroom or 3-7mg/kg of extract per day
best Form
Extract standardized for D-fraction
timing
With meals
safety Rating
Generally Safe

Overview

Maitake mushroom (Grifola frondosa) is an edible mushroom that grows at the base of trees, particularly oaks. It is native to Japan, China, and North America. Maitake has been used in traditional Chinese and Japanese medicine for centuries to enhance the immune system. It is rich in beta-glucans, which are complex sugars that have been shown to have immune-modulating effects. Maitake is also being studied for its potential role in cancer therapy and for its ability to help regulate blood sugar levels.

Key Benefits

Immune Modulation

Maitake contains beta-glucans that can help to stimulate the immune system.

Blood Sugar Regulation

Some studies suggest that maitake may help to improve insulin sensitivity and lower blood sugar levels.

Anti-Cancer Properties

Maitake is being studied for its potential to inhibit the growth of cancer cells.

Dosage & How to Take

Dosage can vary depending on the form and concentration of the supplement.

PurposeDoseNotes
Immune support1-3g of dried mushroomTaken daily.
Blood sugar regulation500-1500mg of extractTaken with meals.

Best Time to Take

Best taken with meals to enhance absorption.

With or Without Food

Yes

Forms & Bioavailability

FormAbsorptionBest ForNotes
Dried mushroomLowCulinary use.Can be added to soups, stews, and other dishes.
ExtractHighTherapeutic effects.Standardized for D-fraction, the active compound.

Side Effects & Safety

Common

  • Stomach upset

Rare

  • Allergic reactions

Contraindications

  • Autoimmune diseases (use with caution).

Interactions

Immunosuppressant drugsModerate

May counteract the effects of these drugs.

Scientific Research

2004Journal of Medicinal Food

Effect of Maitake (Grifola frondosa) D-Fraction on the activation of NK cells in cancer patients

Maitake D-Fraction appears to repress cancer progression and primarily exerts its effect through stimulation of NK activity.

Food Sources

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.