Maitake Extract

Immune-boosting mushroom that also supports blood sugar balance.

Also known as: Grifola frondosa • Hen of the Woods

other Names
Grifola frondosa, Hen of the Woods
primary Benefits
Immune modulation, blood sugar control, cholesterol reduction, anti-cancer properties
common Dose
1-3 grams of extract daily
best Form
Standardized extract containing D-Fraction
timing
With meals
safety Rating
Generally safe with few reported side effects

Overview

Maitake extract comes from the Grifola frondosa mushroom, a large, edible fungus native to Japan, China, and North America. It has been used in traditional medicine for its immune-enhancing and metabolic benefits. Maitake is rich in beta-glucans, which are complex sugars that have been shown to stimulate the immune system and help regulate blood sugar levels.

Key Benefits

Enhances Immune Function

The beta-glucans in Maitake stimulate the activity of immune cells like macrophages, T-cells, and natural killer (NK) cells, strengthening the body's defenses.

Helps Regulate Blood Sugar

Studies suggest that Maitake extract can improve insulin sensitivity and help lower blood glucose levels, making it beneficial for managing diabetes.

May Lower Cholesterol

Research indicates that Maitake can help reduce LDL (bad) cholesterol levels, supporting cardiovascular health.

Possesses Anti-Cancer Properties

Maitake D-Fraction, a specific extract, has been studied for its ability to inhibit tumor growth and enhance the effectiveness of chemotherapy.

Dosage & How to Take

The appropriate dose of Maitake extract depends on the form and the individual's health condition. It is typically taken with meals.

PurposeDoseNotes
Immune Support1-3 grams dailyCan be taken in divided doses.
Blood Sugar Management3-6 grams dailyBest taken before meals.
Adjunctive Cancer Therapy20 mg/kg of body weight of D-Fraction dailyShould be used under the supervision of a healthcare professional.

Best Time to Take

With meals to aid absorption and for blood sugar benefits.

With or Without Food

Yes, it is recommended to take Maitake with food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Standardized Extract CapsulesHighConvenience and precise dosing.Look for extracts standardized for beta-glucans or D-Fraction.
Powdered ExtractHighAdding to food and drinks.Offers flexibility in dosing.
Whole MushroomLowerCulinary purposes.Can be cooked and eaten as part of a meal.

Side Effects & Safety

Common

  • Generally well-tolerated.

Rare

  • Allergic reactions in sensitive individuals.

Contraindications

  • Mushroom allergies.

Interactions

Antidiabetes drugsModerate

May enhance the blood sugar-lowering effect. Monitor blood glucose levels closely.

Blood thinnersMild

May have a mild blood-thinning effect and could increase the risk of bleeding.

Scientific Research

2013Journal of Medicinal Food

Maitake D-Fraction: a new potential protector against breast cancer

Maitake D-Fraction was shown to suppress tumor growth in a mouse model of breast cancer.

2007Journal of Pharmacy and Pharmacology

Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice

An alpha-glucan from Maitake was found to lower blood glucose levels and improve insulin resistance in diabetic mice.

Food Sources

Maitake Mushroom (Grifola frondosa)

Products With Maitake Extract

1 product in our database contains this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.