Lion's Mane Extract
A medicinal mushroom that stimulates nerve growth factor for brain health and cognitive support.
Also known as: Hericium erinaceus • Yamabushitake • Monkey Head Mushroom
Overview
Lion's Mane (Hericium erinaceus) is a culinary and medicinal mushroom known for its unique ability to stimulate the production of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). These neurotrophins are essential for the growth, maintenance, and survival of neurons. Research suggests Lion's Mane may support cognitive function, memory, and nerve regeneration.
Key Benefits
Nerve Growth Factor Stimulation
Hericenones and erinacines in Lion's Mane cross the blood-brain barrier and stimulate NGF synthesis.
Cognitive Enhancement
Clinical trials show improved cognitive function scores in older adults with mild cognitive impairment.
Neuroprotection
May protect against neurodegenerative conditions by reducing oxidative stress and inflammation in neural tissue.
Mood Support
Studies suggest reductions in anxiety and depression symptoms with regular supplementation.
Dosage & How to Take
500-3000 mg daily of extract.
| Purpose | Dose | Notes |
|---|---|---|
| General cognitive support | 500-1000 mg/day | Dual extract |
| Therapeutic/neurological | 1000-3000 mg/day | Split into 2-3 doses |
Best Time to Take
Morning or with meals.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Dual Extract (Hot Water + Ethanol) | High | Full spectrum of compounds | Extracts both water-soluble and fat-soluble actives. |
| Fruiting Body Capsules | Moderate | Standard supplementation | Ensure it's fruiting body, not mycelium on grain. |
| Powder | Moderate | Adding to coffee/smoothies | Mild flavor. |
Side Effects & Safety
Common
- Mild digestive discomfort initially
Rare
- Skin rash in those with mushroom allergies
Contraindications
- Mushroom allergy
- Caution with blood thinners
Interactions
May have mild antiplatelet activity.
May lower blood sugar.
Scientific Research
Lion's Mane and cognitive function
RCT showed significant improvement in cognitive function scores in elderly subjects with mild cognitive impairment after 16 weeks.
Food Sources
Products With Lion's Mane Extract
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.