Lactoferrin
An iron-binding protein with antimicrobial and immune-modulating properties.
Also known as: Apolactoferrin
Overview
Lactoferrin is a glycoprotein that is naturally present in milk and other bodily fluids, such as saliva and tears. It is an iron-binding protein, meaning it can bind to and transport iron in the body. This property also gives it antimicrobial activity, as it can sequester iron that is essential for the growth of many pathogenic bacteria. In addition to its antimicrobial effects, lactoferrin has been shown to have immune-modulating properties, helping to regulate the immune system's response to infection and inflammation. It is often used as a supplement to support immune function, gut health, and iron absorption.
Key Benefits
Supports Immune Function
Lactoferrin has been shown to have immune-modulating effects, helping to regulate the immune system.
Antimicrobial Properties
By binding to iron, lactoferrin can inhibit the growth of pathogenic bacteria.
Promotes Gut Health
Lactoferrin may help promote the growth of beneficial bacteria in the gut and reduce inflammation.
Dosage & How to Take
Dosage can vary depending on the intended use. It is often taken in divided doses.
| Purpose | Dose | Notes |
|---|---|---|
| Immune Support | 200-400 mg per day | Can be taken in divided doses. |
| Gut Health | 200-400 mg per day | Can be taken in divided doses. |
Best Time to Take
Can be taken with or without food.
With or Without Food
Optional
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Lactoferrin | High | General supplementation. | The standard form of lactoferrin. |
| Apolactoferrin | High | Enhanced antimicrobial activity. | The iron-free form of lactoferrin. |
Side Effects & Safety
Common
- Diarrhea
- Nausea
- Constipation
Rare
- Skin rash
- Loss of appetite
Contraindications
- Individuals with a milk allergy should avoid lactoferrin supplements derived from cow's milk.
Interactions
No significant interactions have been reported.
Scientific Research
Lactoferrin: A Natural Glycoprotein with Multiple Functions
Lactoferrin has a wide range of biological functions, including antimicrobial, antiviral, and immunomodulatory activities.
The effect of lactoferrin on the gut microbiota: a systematic review
Lactoferrin supplementation may have a positive effect on the gut microbiota.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.