L. plantarum (IBS-studied)
A specific probiotic strain clinically studied for its benefits in managing Irritable Bowel Syndrome (IBS) symptoms.
Also known as: Lactiplantibacillus plantarum • LP299V
Overview
Lactobacillus plantarum, particularly the strain 299v (LP299V), is one of the most well-researched probiotics for digestive health. It has been the subject of numerous clinical trials investigating its efficacy in alleviating the symptoms of Irritable Bowel Syndrome (IBS), such as abdominal pain, bloating, and irregular bowel habits. It works by adhering to the intestinal lining, promoting a healthy gut barrier, and modulating the gut microbiota.
Key Benefits
Alleviates IBS Symptoms
Multiple studies have shown that L. plantarum 299v can significantly reduce the frequency and severity of abdominal pain and bloating in individuals with IBS.
Improves Bowel Regularity
This strain can help normalize bowel movements, providing relief from both constipation and diarrhea-predominant IBS.
Strengthens Gut Barrier Function
L. plantarum helps to maintain the integrity of the intestinal wall, which can be compromised in individuals with IBS.
Dosage & How to Take
The effective dose of L. plantarum for IBS symptoms is typically in the range of 10 to 20 billion Colony Forming Units (CFUs) per day.
| Purpose | Dose | Notes |
|---|---|---|
| IBS Symptom Management | 10-20 Billion CFU/day | Strain 299v is the most studied for this purpose. |
| General Gut Health | 5-10 Billion CFU/day | Can be taken as part of a multi-strain probiotic formula. |
Best Time to Take
Can be taken at any time of day, with or without a meal. Consistency is key.
With or Without Food
Taking with food may slightly improve survival through the digestive tract, but it is not essential.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules | High | Targeted delivery | Enteric-coated capsules protect the probiotics from stomach acid. |
| Powder | High | Mixing into food or drinks | Good for those who have difficulty swallowing pills. |
Side Effects & Safety
Common
- Mild gas or bloating during the first few days of use
Rare
- Allergic reactions (very rare)
Contraindications
- Severely immunocompromised individuals should consult a doctor before taking probiotics.
Interactions
Antibiotics can kill probiotics. Take probiotics at least 2-3 hours apart from antibiotics.
Theoretically, probiotics could pose a risk in those on immunosuppressive therapy. Consult a physician.
Scientific Research
Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.
A 4-wk treatment with L. plantarum 299v provided effective symptom relief, particularly of abdominal pain and bloating, in IBS patients.
Lactobacillus plantarum 299v: a review of its anti-inflammatory and immunomodulatory properties
LP299V has demonstrated an ability to modulate the immune system and reduce inflammation in the gut.
Food Sources
Products With L. plantarum (IBS-studied)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.