KSM-66 Ashwagandha Root Extract (5% Withanolides)
A powerful adaptogen that helps the body manage stress and promotes a sense of calm and well-being.
Also known as: Ashwagandha • Withania somnifera • Indian ginseng
Overview
KSM-66 is a branded, full-spectrum extract of ashwagandha root with a high concentration of withanolides. It is one of the most clinically studied forms of ashwagandha and is known for its ability to reduce stress, enhance memory and cognitive function, and improve physical performance.
Key Benefits
Reduces Stress and Anxiety
Clinically shown to reduce levels of the stress hormone cortisol, leading to a reduction in stress and anxiety.
Enhances Cognitive Function
Improves memory, focus, and information processing speed.
Improves Physical Performance
Increases strength, muscle size, and endurance, while also reducing exercise-induced muscle damage.
Dosage & How to Take
The standard dose for KSM-66 is 300 mg taken twice daily. It can be taken with or without food.
| Purpose | Dose | Notes |
|---|---|---|
| Stress Reduction | 300-600 mg | Divided into two daily doses. |
| Cognitive Enhancement | 600 mg | Taken as a single dose or divided. |
| Physical Performance | 600 mg | Taken daily. |
Best Time to Take
Can be taken in the morning to support daytime energy and focus, or in the evening to promote restful sleep.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| KSM-66 Root Extract | High | Clinically studied and standardized for withanolide content. | The most researched form of ashwagandha. |
| Whole Root Powder | Medium | A less concentrated form that may still offer benefits. | Less potent than standardized extracts. |
Side Effects & Safety
Common
- Mild drowsiness, upset stomach
Rare
- Headache, nausea
Contraindications
- Pregnant or breastfeeding women should avoid ashwagandha. Individuals with autoimmune diseases should consult a doctor before use.
Interactions
Ashwagandha may decrease the effectiveness of immunosuppressant drugs.
May increase the effects of sedative medications.
Scientific Research
A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults
KSM-66 significantly reduced stress and cortisol levels.
Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Memory and Cognitive Functions
Ashwagandha root extract improved memory and cognitive function in adults with mild cognitive impairment.
Food Sources
Products With KSM-66 Ashwagandha Root Extract (5% Withanolides)
6 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.