Iron Bisglycinate
A highly absorbable and stomach-friendly form of iron for treating anemia without the constipation.
Also known as: Ferrous Bisglycinate Chelate • Gentle Iron
Overview
Iron is an essential mineral for producing hemoglobin, the protein in red blood cells that carries oxygen throughout the body. Iron deficiency is common, especially in women, leading to fatigue, weakness, and anemia. Iron bisglycinate is a chelated form of iron, meaning the iron molecule is bound to two molecules of the amino acid glycine. This chelation makes it highly bioavailable and much gentler on the digestive system than traditional iron salts like ferrous sulfate, significantly reducing side effects like constipation and nausea.
Key Benefits
High Bioavailability
The chelated form protects the iron from factors in the gut that inhibit absorption, leading to more iron being absorbed by the body.
Gentle on the Stomach
Does not cause the constipation, nausea, and stomach upset commonly associated with other forms of iron.
Corrects Iron-Deficiency Anemia
Effectively raises hemoglobin and ferritin levels to combat fatigue, weakness, and shortness of breath.
Supports Energy Levels
By improving oxygen transport, it helps reduce tiredness and fatigue.
Dosage & How to Take
Dosage should be based on blood test results and a doctor's recommendation.
| Purpose | Dose | Notes |
|---|---|---|
| General Supplementation (Women) | 18 mg/day | This is the RDA for menstruating women. |
| Treating Deficiency | 25-60 mg/day or higher | Must be guided by a healthcare professional. |
Best Time to Take
For best absorption, take on an empty stomach. If it causes mild upset, take with a small amount of food.
With or Without Food
Avoid taking with calcium, tea, or coffee as they inhibit absorption. Taking with Vitamin C enhances absorption.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Iron Bisglycinate Chelate | Very High | Everyone, especially those with sensitive stomachs | The superior form for oral iron supplementation. |
Side Effects & Safety
Common
- Far less common than other iron forms, but may include mild nausea or dark stools.
Rare
- Allergic reactions.
Contraindications
- Hemochromatosis (iron overload disorder).
- Keep out of reach of children to prevent accidental overdose.
Interactions
Iron can decrease the absorption of these antibiotics. Separate doses by at least 2 hours.
Iron can decrease the absorption of levothyroxine. Separate doses by at least 4 hours.
Scientific Research
Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial
Iron bisglycinate was as effective as a double dose of iron sulfate in preventing anemia, with significantly fewer gastrointestinal side effects.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.