Icariin

The active compound in horny goat weed, known for its aphrodisiac effects.

Also known as: Horny Goat Weed Extract

other Names
Horny Goat Weed Extract
primary Benefits
Erectile dysfunction, libido enhancement, bone health
common Dose
60-1000 mg per day
best Form
Standardized extract
timing
Can be taken daily or as needed
safety Rating
Moderate Caution

Overview

Icariin is the primary active compound found in plants of the Epimedium genus, most notably Horny Goat Weed. It is a flavonoid compound that has been traditionally used in Chinese medicine to enhance libido and treat erectile dysfunction. Icariin is believed to work by inhibiting the enzyme PDE5, which is the same mechanism of action as prescription drugs like sildenafil. By inhibiting PDE5, icariin can increase blood flow to the penis, resulting in improved erections. In addition to its effects on sexual health, icariin is also being studied for its potential to improve bone health, protect the brain, and reduce inflammation.

Key Benefits

Improves Erectile Function

Icariin is a natural PDE5 inhibitor that can help to improve blood flow and erectile function.

Enhances Libido

It is believed to have aphrodisiac properties that can increase sexual desire in both men and women.

Supports Bone Health

Some research suggests that icariin may help to improve bone density and reduce the risk of osteoporosis.

Dosage & How to Take

A typical dose of icariin is 60-1000 mg per day, depending on the concentration of the extract.

PurposeDoseNotes
Erectile Dysfunction200-1000 mg per dayStandardized to contain at least 10% icariin.
Libido Enhancement60-200 mg per dayMay be taken as needed.

Best Time to Take

Can be taken daily or as needed before sexual activity.

With or Without Food

Best taken with food to reduce the risk of stomach upset.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Standardized ExtractHighEnsuring a consistent dose of icariin.Look for extracts standardized to contain 10-60% icariin.
Capsules/TabletsMediumConvenience.May not be standardized.

Side Effects & Safety

Common

  • Dizziness
  • vomiting
  • dry mouth
  • thirst
  • nosebleed

Rare

  • Spasms and severe breathing problems

Contraindications

  • Avoid if you have a bleeding disorder, low blood pressure, or are pregnant or breastfeeding.

Interactions

Blood pressure medicationModerate

Icariin may lower blood pressure, so it could increase the effects of blood pressure-lowering drugs.

Blood thinnersModerate

Icariin may slow blood clotting, so it could increase the risk of bleeding when taken with blood-thinning medications.

Scientific Research

2008The Journal of Sexual Medicine

Icariin for erectile dysfunction

A study in rats showed that icariin was effective at improving erectile function.

2007Journal of Bone and Mineral Research

Icariin and bone health

A study in postmenopausal women found that a daily supplement of icariin helped to decrease bone loss.

Food Sources

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.