Hydroxycitric Acid
A compound found in Garcinia cambogia that may aid in weight loss.
Also known as: HCA • Garcinia cambogia
Overview
Hydroxycitric acid (HCA) is a compound extracted from the rind of the Garcinia cambogia fruit. It has been promoted as a weight loss supplement due to its purported ability to block the enzyme ATP citrate lyase, which is involved in the formation of fat. By inhibiting this enzyme, HCA may help to reduce fat storage and increase fat burning. It is also believed to increase levels of the neurotransmitter serotonin, which may help to suppress appetite and reduce food cravings. However, the evidence for the effectiveness of HCA for weight loss is mixed, and some studies have shown no benefit. It is important to note that HCA is not a magic bullet for weight loss and should be used in conjunction with a healthy diet and exercise program.
Key Benefits
May Aid in Weight Loss
HCA may help to reduce fat storage and increase fat burning, which could lead to weight loss.
Suppresses Appetite
By increasing serotonin levels, HCA may help to reduce appetite and food cravings.
Dosage & How to Take
A typical dose of HCA is 500-1500 mg per day, taken in divided doses.
| Purpose | Dose | Notes |
|---|---|---|
| Weight Loss | 500-1000 mg | Taken 30-60 minutes before each meal. |
| Appetite Suppression | 500 mg | Taken before meals as needed. |
Best Time to Take
For best results, take HCA 30-60 minutes before meals.
With or Without Food
Should be taken on an empty stomach.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Standardized Extract | High | Ensuring a consistent dose of HCA. | Look for extracts standardized to contain 50-60% HCA. |
| Capsules/Tablets | Medium | Convenience. | May not be standardized. |
Side Effects & Safety
Common
- Dizziness
- headache
- dry mouth
- diarrhea
- nausea
Rare
- Liver damage
Contraindications
- Avoid if you have liver or kidney problems, or are pregnant or breastfeeding.
Interactions
HCA may lower blood sugar, so it could increase the effects of diabetes medications.
HCA may increase the risk of rhabdomyolysis, a rare but serious side effect of statins.
Scientific Research
HCA for weight loss
A review of studies found that HCA had a small but statistically significant effect on weight loss.
HCA and appetite
Some studies have shown that HCA can help to reduce appetite and food intake.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.