Hyaluronic Acid (Oral)
The body's 'nature's moisturizer,' which lubricates joints and hydrates tissues.
Also known as: HA • Hyaluronan • Sodium Hyaluronate
Overview
Hyaluronic Acid (HA) is a glycosaminoglycan, a long, unbranched carbohydrate, that is a key component of synovial fluid—the viscous fluid that cushions and lubricates joints. It is also a major component of skin and connective tissue. While HA injections are a common medical treatment for osteoarthritis, oral supplementation with specific molecular weights of HA has also been shown to be effective. The body can absorb oral HA, which then travels to the joints, helping to increase the viscosity of synovial fluid and reduce inflammation.
Key Benefits
Improves Joint Lubrication
Increases the viscoelasticity of synovial fluid, providing better cushioning and shock absorption.
Reduces Pain and Improves Function
Multiple studies have confirmed that oral HA can significantly reduce the symptoms of osteoarthritis.
Supports Skin Health
As a powerful humectant, it helps skin retain moisture, reducing the appearance of fine lines and wrinkles.
Dosage & How to Take
The effective dose for joint health is typically between 120mg and 240mg per day.
| Purpose | Dose | Notes |
|---|---|---|
| Knee Osteoarthritis | 200mg/day | Studies show benefits with consistent use over several months. |
| Skin Hydration | 120mg/day | Can improve skin moisture and texture. |
Best Time to Take
Can be taken at any time of day.
With or Without Food
Not required.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Sodium Hyaluronate | Good | General joint and skin support. | This is the salt form of HA, which is stable and commonly used in supplements. |
Side Effects & Safety
Common
- None, it is very well tolerated.
Rare
- None known.
Contraindications
- None known, but those with a history of cancer should consult a doctor as HA can be involved in cell proliferation.
Interactions
Scientific Research
Oral hyaluronan relieves knee pain: a review
A review of clinical studies concluded that oral administration of HA has a favorable effect on knee osteoarthritis symptoms.
Food Sources
Products With Hyaluronic Acid (Oral)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.