Growth Factors (IGF-1)
A key hormone that mediates the effects of growth hormone, promoting tissue growth and development.
Also known as: Insulin-Like Growth Factor-1 • Somatomedin C
Overview
Insulin-Like Growth Factor-1 (IGF-1) is a hormone that, along with growth hormone (GH), helps promote normal bone and tissue growth and development. It is produced primarily by the liver and circulates in the bloodstream. IGF-1 is crucial for childhood growth and continues to have anabolic effects in adults.
Key Benefits
Promotes Muscle Growth
IGF-1 stimulates muscle protein synthesis and the proliferation of muscle cells, leading to increased muscle mass.
Enhances Tissue Repair
It plays a vital role in the regeneration and repair of various tissues, including muscle, bone, and cartilage.
Supports Bone Health
IGF-1 is essential for bone growth and mineralization, contributing to strong and healthy bones.
Dosage & How to Take
IGF-1 is a potent hormone and should only be used under the guidance of a qualified healthcare professional. Dosages are highly individualized and depend on various factors, including age, sex, and medical condition.
| Purpose | Dose | Notes |
|---|---|---|
| Growth Hormone Deficiency | Prescribed by a doctor | Administered via injection. |
| Anti-Aging and Performance Enhancement | Varies, often in the range of 20-100mcg per day | Use for these purposes is controversial and carries risks. |
Best Time to Take
Typically administered as a subcutaneous injection, with timing determined by a healthcare provider.
With or Without Food
N/A (injectable)
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Injectable IGF-1 | High | Medical treatment | Requires a prescription and medical supervision. |
| IGF-1 Precursors/Boosters | Varies | Supporting natural production | Supplements containing ingredients like deer antler velvet or colostrum are purported to increase IGF-1 levels. |
Side Effects & Safety
Common
- Hypoglycemia (low blood sugar)
- Joint pain
- Water retention
Rare
- Acromegaly (abnormal growth of hands, feet, and face)
- Increased risk of certain cancers
Contraindications
- Active cancer
- Benign intracranial hypertension
Interactions
Increases the risk of hypoglycemia.
IGF-1 mediates the effects of GH, and their combined use can have synergistic effects.
Scientific Research
The role of IGF-1 in growth and development
IGF-1 is a critical mediator of growth hormone's effects on somatic growth.
IGF-1 and muscle regeneration
IGF-1 plays a key role in muscle regeneration by promoting the proliferation and differentiation of muscle satellite cells.
Food Sources
Products With Growth Factors (IGF-1)
1 product in our database contains this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.