DMAE
A compound that may support brain health, improve mood, and enhance skin firmness.
Also known as: Dimethylaminoethanol • Deanol
Overview
DMAE (Dimethylaminoethanol) is a compound that is produced in small amounts in the brain and can also be found in fatty fish like salmon and sardines. It is believed to work by increasing the production of acetylcholine, a neurotransmitter that is crucial for memory and learning. DMAE is taken as a supplement to support cognitive function, improve mood, and is also used topically in skincare products for its potential skin-firming effects.
Key Benefits
May Improve Cognitive Function
By potentially increasing acetylcholine levels, DMAE may help improve focus, memory, and overall mental clarity.
Can Enhance Mood
Some users report a mild stimulant effect, leading to improved mood and reduced feelings of apathy.
Firms and Tightens Skin
When applied topically, DMAE has been shown to help improve skin firmness and reduce the appearance of fine lines and sagging.
May Reduce Symptoms of ADHD
Older studies suggested a benefit for attention deficit-hyperactivity disorder (ADHD), though more recent research is lacking.
Dosage & How to Take
Oral DMAE is typically sold as DMAE bitartrate. It is best to start with a low dose and increase gradually.
| Purpose | Dose | Notes |
|---|---|---|
| Cognitive Support | 100-250 mg/day | Taken in the morning. |
| Mood Enhancement | 150-300 mg/day | Higher doses may cause overstimulation. |
Best Time to Take
Due to its potential stimulant effects, it is best to take DMAE in the morning to avoid interference with sleep.
With or Without Food
Can be taken with or without food.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Capsules/Tablets (DMAE Bitartrate) | Good | Oral supplementation for cognitive and mood benefits. | The most common form. |
| Topical Creams/Serums | N/A | Skincare applications to improve skin firmness. | Often combined with other anti-aging ingredients. |
Side Effects & Safety
Common
- Headache
- Insomnia
- Muscle tension
- Vivid dreams
Rare
- Increased blood pressure
- Confusion
- Hypomania
Contraindications
- Should not be used by individuals with bipolar disorder, schizophrenia, or seizure disorders. Pregnant or breastfeeding women should also avoid DMAE.
Interactions
DMAE may counteract the effects of these medications.
May increase the effects and side effects of these medications.
Theoretically, DMAE could affect blood clotting, so caution is advised.
Scientific Research
The role of dimethylaminoethanol in cosmetic dermatology
A review of studies suggests that topical DMAE can increase skin firmness and reduce the appearance of lines and wrinkles.
Placebo-controlled study of DMAE in tardive dyskinesia
An older study found that DMAE was effective in reducing symptoms of tardive dyskinesia, a movement disorder.
Food Sources
Products With DMAE
2 products in our database contain this ingredient
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.