Deglycyrrhizinated Licorice (DGL)

The safe form of licorice for healing the stomach lining.

Also known as: DGL • Glycyrrhiza glabra

other Names
DGL
primary Benefits
Heals stomach ulcers, soothes heartburn
common Dose
300-400 mg chewable tablet before meals
best Form
Chewable tablets
timing
15-20 minutes before meals
safety Rating
Very Safe

Overview

Deglycyrrhizinated licorice, or DGL, is a form of licorice root that has had glycyrrhizin removed. Glycyrrhizin is the compound responsible for the potential side effects of licorice, such as high blood pressure and low potassium levels. DGL retains the beneficial compounds that help heal the stomach lining, making it a safe and effective remedy for peptic ulcers, acid reflux, and gastritis. It works by increasing mucus production, which protects the stomach from acid.

Key Benefits

Heals Peptic Ulcers

Studies have shown DGL is as effective as some medications for healing stomach and duodenal ulcers.

Reduces GERD/Acid Reflux

Increases the protective mucous lining of the esophagus and stomach.

Fights H. pylori

May inhibit the growth of the H. pylori bacteria, a common cause of ulcers.

Dosage & How to Take

300-400 mg per tablet.

PurposeDoseNotes
Ulcer healing1-2 chewable tablets 20 mins before mealsChewing is essential for effectiveness.
Heartburn relief1 tablet as needed before meals or at bedtimeMust be mixed with saliva to be activated.

Best Time to Take

Take 15-20 minutes before each meal.

With or Without Food

No, must be taken before food.

Forms & Bioavailability

FormAbsorptionBest ForNotes
Chewable TabletsHighAll applicationsThis is the only proven effective form.
Capsules/PowderLowNot recommendedDoes not allow for mixing with saliva.

Side Effects & Safety

Common

  • None reported

Rare

  • None reported

Contraindications

  • None, as the problematic glycyrrhizin is removed.

Interactions

None knownNone

DGL is considered very safe and does not have the interactions of whole licorice.

Scientific Research

1982The Irish Medical Journal

DGL and Peptic Ulcers

A landmark study showed DGL was as effective as the drug cimetidine in healing gastric ulcers, with no side effects.

Food Sources

Products With Deglycyrrhizinated Licorice (DGL)

2 products in our database contain this ingredient

Frequently Asked Questions

Medical Disclaimer

This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.