Cobalt
An essential trace element as the core of vitamin B12.
Also known as: Co • Cobalamin component
Overview
Cobalt is an essential trace element that forms the central atom of vitamin B12 (cobalamin). In this form, cobalt is vital for red blood cell formation, neurological function, and DNA synthesis. However, inorganic cobalt supplements are not recommended as the body can only use cobalt in the form of vitamin B12.
Key Benefits
Vitamin B12 Component
Cobalt is the central metal ion in vitamin B12, essential for nerve function and red blood cell production.
DNA Synthesis
As part of B12, cobalt participates in DNA synthesis and methylation reactions.
Dosage & How to Take
Cobalt should only be consumed as vitamin B12. The RDA for B12 is 2.4 mcg/day for adults.
| Purpose | Dose | Notes |
|---|---|---|
| As vitamin B12 | 2.4-1000 mcg B12/day | Higher doses for deficiency |
Best Time to Take
With meals.
With or Without Food
Yes.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Methylcobalamin (B12) | High | Active form of B12 | Preferred form for supplementation. |
| Cyanocobalamin (B12) | Good | Most studied form | Requires conversion to active forms. |
Side Effects & Safety
Common
- Well tolerated as B12
Rare
- Inorganic cobalt supplements can cause cardiomyopathy, thyroid dysfunction
Contraindications
- Do not take inorganic cobalt supplements
Interactions
Cobalt can interfere with iron absorption at high doses.
Scientific Research
Cobalt toxicity from supplements
Case reports of cardiomyopathy and hypothyroidism from inorganic cobalt supplementation.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.