Cissus Quadrangularis
An ancient medicinal plant revered for its ability to accelerate bone healing and support joint health.
Also known as: Veldt Grape • Devil's Backbone • Hadjod
Overview
Cissus quadrangularis is a succulent vine from the grape family, traditionally used in Ayurvedic medicine for healing broken bones and injured ligaments. It is rich in carotenoids, triterpenoids, and ascorbic acid. Research suggests that it acts as a bone-building agent by influencing early regeneration of connective tissue and enhancing the mineralization process. It is also believed to have analgesic and anti-inflammatory properties, making it beneficial for joint pain.
Key Benefits
Speeds Up Bone Healing
Studies show it can reduce the time it takes for bone fractures to heal by up to 50%.
Strengthens Bones
Appears to shift the balance from bone breakdown to bone building, increasing bone density.
Reduces Joint Pain
Exhibits analgesic properties that can help alleviate pain associated with exercise-induced joint injury.
Dosage & How to Take
A common dosage is 500mg of a standardized extract taken twice daily.
| Purpose | Dose | Notes |
|---|---|---|
| Fracture Healing | 500-750mg twice daily | Start as soon as possible after injury. |
| Joint Pain/Bone Density | 500mg twice daily | Consistent use is key. |
Best Time to Take
Can be taken with meals or on an empty stomach.
With or Without Food
Not required.
Forms & Bioavailability
| Form | Absorption | Best For | Notes |
|---|---|---|---|
| Standardized Ketosterone Extract | Good | Bone fractures and joint support. | Look for extracts standardized to 2.5-5% total ketosterones. |
Side Effects & Safety
Common
- Headache, intestinal gas, dry mouth (infrequent).
Rare
- Insomnia.
Contraindications
- Not recommended for pregnant or breastfeeding women due to lack of research. Caution in diabetics as it may lower blood sugar.
Interactions
May have an additive blood sugar-lowering effect.
Scientific Research
The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress
While this study focused on weight loss, it highlights the anti-inflammatory and metabolic benefits of Cissus, which are relevant to joint health.
Food Sources
Frequently Asked Questions
Medical Disclaimer
This content is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications. The statements on this page have not been evaluated by the Food and Drug Administration.